Comparing Imaginal Exposure and Imagery Rescripting in Treatment of Posttraumatic Stress Disorder (PTSD) - Full Text View

Sponsors and Collaborators:	Modum Bad University of Oslo
Information provided by:	Modum Bad
ClinicalTrials.gov Identifier:	NCT00891098

Purpose

The outcome of trauma treatment (Posttraumatic Stress Disorder - PTSD) may be influenced by which emotions that are predominant among current symptoms, e.g. fear, anger, guilt, shame. Different treatment procedures for processing traumatic memories may resolve different emotions. This study compares two different treatment procedures of working with trauma memories in PTSD treatment (namely, Imaginal Exposure and Imagery Rescripting) in order to test this.

Condition	Intervention
Posttraumatic Stress Disorder	Behavioral: Imaginal exposure Behavioral: Imagery rescripting

MedlinePlus related topics: Injuries Memory Post-Traumatic Stress Disorder Wounds

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment, Randomized, Single Blind (Outcomes Assessor), Active Control, Parallel Assignment, Efficacy Study
Official Title:	Comparing Imaginal Exposure (IE) and Imagery Rescripting and Reprocessing Therapy (IRRT) in the Treatment of Posttraumatic Stress Disorder (PTSD)

Further study details as provided by Modum Bad:

Primary Outcome Measures:

PTSD symptoms [ Time Frame: pretreatment, weekly during treatment, posttreatment, followup ] [ Designated as safety issue: No ]

Secondary Outcome Measures:

General psychiatric symptoms [ Time Frame: pretreatment, weekly during treatment, postttreatment, followup ] [ Designated as safety issue: No ]

Estimated Enrollment:	64
Study Start Date:	November 2008
Estimated Study Completion Date:	November 2012
Estimated Primary Completion Date:	November 2012 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
Imaginal exposure: Active Comparator	Behavioral: Imaginal exposure 7 individual sessions of imaginal exposure of trauma memories according to the prolonged exposure treatment manual
Imagery rescripting: Experimental	Behavioral: Imagery rescripting 7 individual sessions of imagery rescripting of trauma memories according to the imagery rescripting and reprocessing therapy manual

Detailed Description:

The main objectives of this study are:

To assess the relative efficacy of the two procedures in inpatient treatment for PTSD
To assess whether the predominant emotions in the traumatic memories moderate the outcome of the different procedures
To assess whether theory-derived constructs mediate outcome and whether the mediating relationships are different in the two treatments
To provide a theoretical account of the two models
To psychometrically evaluate 3 new measures

Eligibility

Ages Eligible for Study:	20 Years to 65 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

DSM-IV diagnosis of PTSD identified as primary diagnosis
Accepts withdrawal of all psychotropic medication

Exclusion Criteria:

Extensive dissociative symptoms or current psychosis,
Current suicidal risk,
Extensive current substance or alcohol abuse, or
Ongoing trauma

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00891098

Locations

Norway, Buskerud
Modum Bad
Vikersund, Buskerud, Norway, 3370

Sponsors and Collaborators

Modum Bad

University of Oslo

Investigators

Study Chair:

Asle Hoffart, PhD

Modum Bad and University of Oslo

More Information

No publications provided

Responsible Party:	Modum Bad ( Asle Hoffart, PhD. )
Study ID Numbers:	2-Hoffart
Study First Received:	April 30, 2009
Last Updated:	April 30, 2009
ClinicalTrials.gov Identifier:	NCT00891098 History of Changes
Health Authority:	Norway: The National Committees for Research Ethics in Norway

Study placed in the following topic categories:

Anxiety Disorders
Mental Disorders
Stress Disorders, Post-Traumatic
Stress
Stress Disorders, Traumatic

Additional relevant MeSH terms:

Pathologic Processes
Disease
Anxiety Disorders
Mental Disorders

Stress Disorders, Post-Traumatic
Stress
Stress Disorders, Traumatic

ClinicalTrials.gov processed this record on May 07, 2009