Evaluation of Thoracic Tumors With 18F-FMT and 18F-FDG PET-CT A Clinicopathological Study

This study has been completed.

First Received: June 12, 2008 Last Updated: June 16, 2008 History of Changes

Sponsors and Collaborators:	Gunma University J-Pharma
Information provided by:	Gunma University
ClinicalTrials.gov Identifier:	NCT00698373

Purpose

L-[3-18F]-α-methyltyrosine (18F-FMT) is an amino-acid tracer for positron emission tomography (PET). The aim of this study was to determine whether PET-CT with 18F-FMT provides additional information for the preoperative diagnostic workup as compared with 18F-FDG PET. Tumor uptake of 18F-FMT was compared with several immunohistochemical markers including L-type amino acid transporter 1 (LAT1).

Condition
Non-Small Cell Lung Cancer

MedlinePlus related topics: Cancer Lung Cancer

U.S. FDA Resources

Study Type:	Observational
Study Design:	Prospective
Official Title:	Evaluation of Thoracic Tumors With 18F-FMT and 8F-FDG PET-CT: A Clinicopathological Study

Further study details as provided by Gunma University:

Groups/Cohorts
1 PET study

Eligibility

Ages Eligible for Study:	20 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Non-Probability Sample

Study Population

Patients with indeterminate pulmonary nodule suspicious of lung cancer were eligible for this prospective study.

Criteria

Inclusion Criteria:

Patients with indeterminate pulmonary nodule suspicious of lung cancer

Exclusion Criteria:

Patients with other malignancies and those who had received cancer treatment within the past 5 years were excluded.

Contacts and Locations

No Contacts or Locations Provided

More Information

No publications provided

Study ID Numbers:	Molecular FMT imaging
Study First Received:	June 12, 2008
Last Updated:	June 16, 2008
ClinicalTrials.gov Identifier:	NCT00698373 History of Changes
Health Authority:	Japan: Ministry of Health, Labor and Welfare

Keywords provided by Gunma University:

Fluorine-18-α-methyltyrosine,
Positron emission tomography,
Fluorine-18-fluorodeoxyglucose,
Lung cancer,

Study placed in the following topic categories:

Thoracic Neoplasms
Respiratory Tract Diseases
Lung Neoplasms
Lung Diseases
Non-small Cell Lung Cancer

Fluorides
Carcinoma, Non-Small-Cell Lung
Neoplasms, Glandular and Epithelial
Carcinoma

Additional relevant MeSH terms:

Thoracic Neoplasms
Respiratory Tract Neoplasms
Neoplasms
Neoplasms by Site
Neoplasms by Histologic Type
Respiratory Tract Diseases

Lung Neoplasms
Lung Diseases
Carcinoma, Non-Small-Cell Lung
Neoplasms, Glandular and Epithelial
Carcinoma

ClinicalTrials.gov processed this record on May 07, 2009