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Sponsored by: |
Department of Veterans Affairs |
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Information provided by: | Department of Veterans Affairs |
ClinicalTrials.gov Identifier: | NCT00125242 |
The purpose of this investigation is to further develop and test a treatment for word-finding problems in aphasia. The treatment is designed to strengthen meaning associations within categories of words (e.g., animals, tools, fruits). The treatment is also designed to be used as a search strategy in instances of word-finding difficulty. The study was devised to evaluate the extent to which treatment increases the ability to recall trained, as well as untrained, words.
Condition | Intervention |
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Aphasia Language Disorders Speech Disorders |
Behavioral: Semantic Feature Training |
Study Type: | Interventional |
Study Design: | Treatment, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment, Efficacy Study |
Official Title: | Word-Retrieval for Aphasia: Facilitation of Generalization |
Estimated Enrollment: | 24 |
Study Start Date: | September 2004 |
Estimated Study Completion Date: | June 2009 |
Estimated Primary Completion Date: | June 2009 (Final data collection date for primary outcome measure) |
Arms | Assigned Interventions |
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1
single subject design (24 participants)
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Behavioral: Semantic Feature Training
The treatment is designed to stimulate the semantic feature network so that it may serve as not only a mechanism for improving disrupted lexical semantic processing, but also as a compensatory strategy during word retrieval failures.
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The purpose of the proposed research is to examine the effects of a semantically-oriented treatment on word retrieval in persons with aphasia. The planned investigations are designed to further the development of semantic feature training so that it may serve as not only a mechanism for improving disrupted lexical semantic processing, but also as a compensatory strategy during word retrieval failures. The proposed research will also address the issue of exemplar typicality (Kiran & Thompson, 2003) by examining the effects of training typical versus atypical exemplars of various categories with individuals with different types of aphasia. A series of 24 single subject experimental designs will be conducted in the context of a group design to address the following experimental questions:
Will generalization to untrained typical examples vary across generalization lists that are repeatedly exposed and those that are limited in exposure? (i.e., Does repeated exposure appear to contribute to generalization?)
Ages Eligible for Study: | 21 Years to 75 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
Exclusion Criteria:
Contact: Reuben Walize, MPH | (801) 582-1565 ext 4857 | Reuben.Walize@va.gov |
Contact: Laurence J Meyer, MD PhD | (801) 582-1565 ext 4897 | Laurence.Meyer@va.gov |
United States, Utah | |
VA Salt Lake City Health Care System, Salt Lake City | Recruiting |
Salt Lake City, Utah, United States, 84148 | |
Contact: Reuben Walize, MPH 801-582-1565 ext 4857 Reuben.Walize@va.gov | |
Contact: Laurence J Meyer, MD PhD (801) 582-1565 ext 4897 Laurence.Meyer@va.gov | |
Principal Investigator: Julie L Wambaugh |
Principal Investigator: | Julie L Wambaugh | VA Salt Lake City Health Care System, Salt Lake City |
Responsible Party: | Department of Veterans Affairs ( Wambaugh, Julie - Principal Investigator ) |
Study ID Numbers: | C3826R |
Study First Received: | July 27, 2005 |
Last Updated: | January 29, 2009 |
ClinicalTrials.gov Identifier: | NCT00125242 History of Changes |
Health Authority: | United States: Federal Government |
Aphasia Language therapy Rehabilitation of speech and language disorders Speech-language pathology |
Signs and Symptoms Speech Disorders Aphasia Neurologic Manifestations |
Language Disorders Neurobehavioral Manifestations Communication Disorders |
Signs and Symptoms Speech Disorders Pathologic Processes Disease Aphasia |
Nervous System Diseases Neurologic Manifestations Language Disorders Neurobehavioral Manifestations Communication Disorders |