Homeostatic Sleep Regulation in Older Persons

This study has been completed.

First Received: October 24, 2007 Last Updated: May 28, 2008 History of Changes

Sponsors and Collaborators:	National Institute on Aging (NIA) Brigham and Women's Hospital
Information provided by:	National Institute on Aging (NIA)
ClinicalTrials.gov Identifier:	NCT00601445

Purpose

The purpose of this study is to test the hypothesis that sleep homeostasis, also known as sleep pressure or sleep drive, is different in healthy older and younger individuals.

Condition	Intervention
Healthy Aging	Behavioral: Amount of sleep and wake

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Basic Science, Randomized, Open Label, Parallel Assignment
Official Title:	Homeostatic Sleep Regulation in Older Persons

Further study details as provided by National Institute on Aging (NIA):

Primary Outcome Measures:

Total Sleep Time [ Time Frame: During inpatient study ]

Estimated Enrollment:	58
Study Start Date:	September 1999
Study Completion Date:	March 2004

Intervention Details:

4 groups with different patterns of sleep and wake

Detailed Description:

This was an inpatient study of healthy individuals to determine whether homeostatic "sleep drive" effects on sleep change with healthy aging.

Sleep, performance, and mood were studied on individuals sleeping different lengths of time and during wake periods of different durations.

Eligibility

Ages Eligible for Study:	18 Years to 85 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

Ages 18-30 and 60-85 years
Healthy

Exclusion Criteria:

Any medications
Sleep Disorder

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00601445

Locations

United States, Massachusetts
Brigham and Women's Hospital
Boston, Massachusetts, United States, 02115

Sponsors and Collaborators

National Institute on Aging (NIA)

Brigham and Women's Hospital

Investigators

Principal Investigator:

Elizabeth B Klerman, MD, PhD

Brigham and Women's Hospital

More Information

No publications provided

Study ID Numbers:	AG0090, P01-AG009975 - Project 4
Study First Received:	October 24, 2007
Last Updated:	May 28, 2008
ClinicalTrials.gov Identifier:	NCT00601445 History of Changes
Health Authority:	United States: Federal Government

Keywords provided by National Institute on Aging (NIA):

Changes in sleep with aging

Study placed in the following topic categories:

Healthy

ClinicalTrials.gov processed this record on May 06, 2009