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| Sponsored by: |
National Institute of Mental Health (NIMH) |
|---|---|
| Information provided by: | National Institute of Mental Health (NIMH) |
| ClinicalTrials.gov Identifier: | NCT00060762 |
Purpose
This study will evaluate the long-term effectiveness of interpersonal psychotherapy, behavioral weight loss interventions, and guided self help treatments in treating binge eating disorder (BED).
| Condition | Intervention | Phase |
|---|---|---|
|
Eating Disorders |
Behavioral: Interpersonal Therapy Behavioral: Behavioral Weight Loss Treatment Behavioral: Guided Self Help |
Phase IV |
| Study Type: | Interventional |
| Study Design: | Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Efficacy Study |
| Official Title: | Effectiveness of Psychological Treatments for BED |
| Estimated Enrollment: | 210 |
| Study Start Date: | April 2002 |
| Estimated Study Completion Date: | March 2005 |
BED is a serious condition that is associated with psychiatric comorbidity, psychosocial impairment, and obesity. Interpersonal psychotherapy (IPT), behavioral weight loss (BWL) interventions, and guided self help (GSH) treatments for BED have been evaluated, but the safest and most effective treatment has not yet been identified. This study will determine which of these three treatments is most effective in treating BED.
Participants are stratified by negative affect subtype and are randomly assigned for 6 months to one of three treatment groups: IPT, BWL, or GSH. IPT focuses on current interpersonal problems which are hypothesized to increase negative affect and lead to binge eating. BWL interventions involve the adoption of weight loss inducing behaviors. GSH is a shortened version of cognitive behavioral therapy that focuses directly on eating behavior. IPT and BWL patients have 20 treatment sessions; those receiving GSH have 10 sessions. Assessments are made pre-treatment, post-treatment, and at 6, 12, 18, and 24 months after treatment is complete.
Eligibility| Ages Eligible for Study: | 18 Years to 65 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Contacts and Locations| United States, California | |
| W. Stewart Agras | |
| Stanford, California, United States, 94305 | |
| United States, Missouri | |
| Washington University School of Medicine | |
| St. Louis, Missouri, United States, 63100 | |
| United States, New Jersey | |
| Rutgers University Eating Disorder Clinic | |
| Piscataway, New Jersey, United States, 08854 | |
More Information
| Responsible Party: | Stanford University ( W. Stewart Agras ) |
| Study ID Numbers: | R01 MH63863, DSIR 83-ATAS |
| Study First Received: | May 12, 2003 |
| Last Updated: | November 7, 2008 |
| ClinicalTrials.gov Identifier: | NCT00060762 History of Changes |
| Health Authority: | United States: Federal Government |
|
Weight Loss |
|
Body Weight Bulimia Nervosa Mental Disorders |
Bulimia Weight Loss Eating Disorders |
|
Bulimia Nervosa Pathologic Processes Disease Mental Disorders Eating Disorders |
