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Sponsors and Collaborators: |
University of California, San Diego National Eye Institute (NEI) |
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Information provided by: | University of California, San Diego |
ClinicalTrials.gov Identifier: | NCT00221897 |
A prospective, longitudinal observational cohort study evaluating the relationship between changes in the structure of the eye and the vision loss caused by glaucoma. There are two main parts to the study: 1) Visual Function and 2) Optic Nerve Structure
Condition |
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Primary Open Angle Glaucoma Persons at Risk for Glaucoma |
Study Type: | Observational |
Study Design: | Prospective |
Official Title: | Diagnostic Innovations in Glaucoma Study |
Study Start Date: | April 1995 |
The purpose of the study is:
SPECIFIC AIMS OF DIGS: STRUCTURAL ASSESSMENT Overall Aim: Develop improved methods to 1) detect the onset and progression of structural damage due to glaucoma, and 2) to measure the rate of glaucomatous progression and its determinants, and 3) characterize the relationship between structural and functional change over time. In addition, a major goal of this research is to develop methods to shorten the time frame needed to identify and verify progression of optic disc and retinal nerve fiber damage.
SPECIFIC AIMS OF DIGS: VISUAL FUNCTION Overall Aim: Develop improved measures to detect the onset and progression of glaucoma, to assess treatment effectiveness, and to validate predictive genetic testing using psychophysical measures of visual function.
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
Exclusion Criteria:
Contact: Eunice Williams-Steppe, MA | 858-822-1133 | ewsteppe@glaucoma.ucsd.edu |
Contact: Cecelia Gastelum, MPH | 858-534-6714 | cgastelum@glaucoma.ucsd.edu |
United States, California | |
UCSD, Hamilton Glaucoma Center | Recruiting |
La Jolla, California, United States, 92093-0946 | |
Contact: Eunice Williams-Steppe, MA 858-822-1133 ewsteppe@glaucoma.ucsd.edu | |
Contact: Cecelia Gastelum, MPH 858-534-6714 cgastelum@glaucoma.ucsd.edu | |
Principal Investigator: Pamela A Sample, PhD | |
Principal Investigator: Linda M Zangwill, PhD | |
Sub-Investigator: Robert N Weinreb, MD | |
Sub-Investigator: Felipe Medeiros, MD | |
Sub-Investigator: Christopher Bowd, PhD |
Principal Investigator: | Pamela A Sample, PhD | University of California, San Diego |
Principal Investigator: | Linda Zangwill, PhD | University of California, San Diego |
Study ID Numbers: | RO1-EY08208; RO1-EY11008 |
Study First Received: | September 14, 2005 |
Last Updated: | June 20, 2008 |
ClinicalTrials.gov Identifier: | NCT00221897 History of Changes |
Health Authority: | United States: Institutional Review Board |
Primary open angle glaucoma Glaucoma/pathology Glaucoma/physiopathology Nerve Fibers/pathology Risk factors glaucoma |
Glaucoma Eye Diseases Glaucoma, Open-Angle Hypertension Ocular Hypertension |
Glaucoma Eye Diseases Glaucoma, Open-Angle Ocular Hypertension |