Intraocular Pressure (IOP)Assessed by Dynamic Contour Tonometer (DCT) and Glutamic Acid-Alanine-Tyrosine Terpolymer (GAT)

This study is currently recruiting participants.

Verified by St. Franziskus Hospital, December 2008

First Received: October 31, 2007 Last Updated: December 5, 2008 History of Changes

Sponsored by:	St. Franziskus Hospital
Information provided by:	St. Franziskus Hospital
ClinicalTrials.gov Identifier:	NCT00552019

Purpose

Purpose of this study is to evaluate assessment of the intraocular pressure with the dynamic contour tonometry and the Goldmann applanation tonometry in patients with active anterior uveitis.

Condition
Uveitis Intraocular Pressure

U.S. FDA Resources

Study Type:	Observational
Study Design:	Cohort, Prospective
Official Title:	Inflammatory Changes of Corneal Thickness and Influence on Assessment of Intraocular Pressure

Further study details as provided by St. Franziskus Hospital:

Primary Outcome Measures:

IOP by GAT and DCT [ Time Frame: 3 months after treatment start ]

Biospecimen Retention: None Retained

Biospecimen Description:

Estimated Enrollment:	30
Study Start Date:	October 2007
Estimated Study Completion Date:	December 2008

Detailed Description:

Keratoprecipitates are often found in anterior uveitis. Also elevation of the IOP can be seen in these patients. Goldmann applanation tonometry is the standard technique to assess the IOP but depends on the corneal thickness. Therefore IOP is measured by Goldmann and dynamic contour tonometry and corneal thickness is quantified by Orbscan at active uveitis and after the keratoprecipitates have disappeared.

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Probability Sample

Study Population

tertiary referral center

Criteria

Inclusion Criteria:

active anterior or panuveitis with keratoprecipitates

Exclusion Criteria:

corneal endothelial dystrophy

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00552019

Contacts

Contact: Carsten Heinz, MD

49 251 933080

carsten.heinz@uveitis-zentrum.de

Locations

Germany
Department of Ophthalmology at St.-Franziskus Hospital	Recruiting
Münster, Germany, 48145
Principal Investigator: Carsten Heinz, MD

Sponsors and Collaborators

St. Franziskus Hospital

Investigators

Study Director:

Arnd Heiligenhaus, MD

Department of Ophthalmology at St.-Franziskus Hospital

More Information

Additional Information:

Related Info This link exits the ClinicalTrials.gov site

No publications provided

Study ID Numbers:	2007-405-f-S
Study First Received:	October 31, 2007
Last Updated:	December 5, 2008
ClinicalTrials.gov Identifier:	NCT00552019 History of Changes
Health Authority:	Germany: Federal Ministry of Education and Research

Study placed in the following topic categories:

Uveitis
Eye Diseases

Additional relevant MeSH terms:

Uveal Diseases
Uveitis
Eye Diseases

ClinicalTrials.gov processed this record on May 06, 2009