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| Sponsored by: |
Hospital de Base |
|---|---|
| Information provided by: | Hospital de Base |
| ClinicalTrials.gov Identifier: | NCT00777465 |
Purpose
The purpose of the study is to evaluate if acute kidney injury based on AKIN criteria is an independent predictor of 30-day mortality after cardiac surgery.
| Condition |
|---|
|
Kidney Failure |
| Study Type: | Observational |
| Study Design: | Cohort, Prospective |
| Official Title: | AKIN (Acute Kidney Injury Network) Criteria for Acute Kidney Injury After Cardiac Surgery - Risk Factors, Clinical Outcomes and 30-Day Mortality - Prospective Cohort Study |
| Enrollment: | 1936 |
| Study Start Date: | January 2003 |
| Study Completion Date: | September 2008 |
| Primary Completion Date: | September 2008 (Final data collection date for primary outcome measure) |
| Groups/Cohorts |
|---|
|
AKI (-)
Patients without acute kidney injury after cardiac surgery
|
|
AKI (+)
Patients with acute kidney injury after cardiac surgery
|
One thousand, nine hundred and thirty-six patients will be enrolled in this series and divided into to groups: Group AKI (-) - patients without acute kidney injury after cardiac surgery. Group AKI (+) - patients with acute kidney injury after cardiac surgery. AKI was defined as an absolute increase in serum creatinine (SCr) of more than or equal to 0.3 mg/dl (≥ 26.4 μmol/l) or a percentage increase in SCr of more than or equal to 50% (1.5-fold from baseline). The change in SCr concentration was defined as the difference between immediate postoperative concentration and the highest concentration during the stay in ICU. Risk Factors, Clinical Outcomes and 30-day Mortality will be evaluate in this patients.
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Probability Sample |
Group AKI (-) and AKI (+) selected consecutively after admission in cardiac surgery postoperative care unit
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| Brazil, São Paulo | |
| Hospital de Base | |
| São José do Rio Preto, São Paulo, Brazil, 15090-000 | |
| Study Director: | Lilia N Maia, PhD | São José do Rio Preto Medical School |
More Information
| Responsible Party: | São José do Rio Preto Medical School ( Mauricio N Machado ) |
| Study ID Numbers: | CAAE-3436.0.000.140-08 |
| Study First Received: | October 21, 2008 |
| Last Updated: | October 21, 2008 |
| ClinicalTrials.gov Identifier: | NCT00777465 History of Changes |
| Health Authority: | Brazil: National Committee of Ethics in Research |
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Kidney failure Risk factors Clinical outcomes Coronary artery bypass Cardiac valve surgery |
Coronary artery bypass grafting Cardiac valve surgery Morbidity Mortality |
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Renal Insufficiency Urologic Diseases Kidney Diseases Kidney Failure |
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Renal Insufficiency Urologic Diseases Kidney Diseases Kidney Failure |
