Screening Scottish Swimmers for Asthma and Rhinitis - Full Text View

Sponsored by:	University of Dundee
Information provided by:	University of Dundee
ClinicalTrials.gov Identifier:	NCT00831428

Purpose

The Scottish National and District swimming teams will be screened for asthma and rhinitis using both mannitol challenge and sport-based exercise challenge.

Condition	Intervention
Asthma Rhinitis	Other: no intervention

MedlinePlus related topics: Asthma Exercise and Physical Fitness

Drug Information available for: Mannitol

U.S. FDA Resources

Study Type:	Observational
Study Design:	Cross-Sectional
Official Title:	A Pilot Study to Identify the Prevalence of Exercise- Induced Asthma and Rhinitis in Scottish Swimmers, Using Mannitol Challenge as a Screening Tool.

Further study details as provided by University of Dundee:

Primary Outcome Measures:

mannitol challenge [ Time Frame: This test will be performed once on a district and once on a national squad training day ] [ Designated as safety issue: No ]

Secondary Outcome Measures:

sport-based challenge [ Time Frame: This test will be performed once on a district and once on a national squad training day ] [ Designated as safety issue: No ]
tidal nitric oxide [ Time Frame: This test will be performed prior to entering the pool, and on exiting the pool ] [ Designated as safety issue: No ]
nasal nitric oxide [ Time Frame: This test will be performed prior to entering the pool, and on exiting the pool ] [ Designated as safety issue: No ]
skin prick test [ Time Frame: This test will be performed once on a district and once on a national squad training day ] [ Designated as safety issue: No ]
mini nasal lavage [ Time Frame: This test will be performed prior to entering the pool, and on exiting the pool ] [ Designated as safety issue: No ]

Biospecimen Retention: None Retained

Biospecimen Description:

Estimated Enrollment:	100
Study Start Date:	February 2009
Estimated Study Completion Date:	June 2009
Estimated Primary Completion Date:	June 2009 (Final data collection date for primary outcome measure)

Groups/Cohorts	Assigned Interventions
Scottish swimming team	Other: no intervention this is a screening study, not an interventional study

Eligibility

Ages Eligible for Study:	11 Years to 23 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Non-Probability Sample

Study Population

The Scottish national and district swimming teams

Criteria

Inclusion Criteria:

member of the Scottish national and district swimming team
informed consent obtained

Exclusion Criteria:

pregnant, lactating or planning to become pregnant
concomitant use of medicines (prescribed, over-the-counter or herbal) that may interfere with the trial.
any clinically significant medical condition, as deemed by the clinical investigators, which may endanger the health of the participant or jeopardise the protocol.
inability to comply with the protocol.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00831428

Contacts

Contact: karine L Clearie, MBBS, MRCP	01382 496440 ext 36440	k.clearie@dundee.ac.uk
Contact: Brian J Lipworth, MBchB	01382496440 ext 36440	brianlipworth@googlemail.com

Locations

United Kingdom, Stirlingshire
The national swimming academy in Stirling
Stirling, Stirlingshire, United Kingdom, FK9 4LA

Sponsors and Collaborators

University of Dundee

Investigators

Principal Investigator:	Karine L Clearie, MBBS, MRCP	Asthma and Allergy Research Group
Study Director:	Brian J Lipworth, MBchB	Asthma and Allergy Research Group

More Information

No publications provided

Responsible Party:	Asthma and Allergy Research Group ( Dr Karine Clearie )
Study ID Numbers:	CLE004
Study First Received:	January 28, 2009
Last Updated:	January 28, 2009
ClinicalTrials.gov Identifier:	NCT00831428 History of Changes
Health Authority:	United Kingdom: Research Ethics Committee

Keywords provided by University of Dundee:

asthma
rhinitis
swimmers
mannitol

Study placed in the following topic categories:

Otorhinolaryngologic Diseases
Bronchial Diseases
Asthma
Rhinitis
Asthma, Exercise-Induced
Lung Diseases, Obstructive
Hypersensitivity

Respiratory Tract Diseases
Respiratory Tract Infections
Mannitol
Lung Diseases
Hypersensitivity, Immediate
Respiratory Hypersensitivity

Additional relevant MeSH terms:

Otorhinolaryngologic Diseases
Bronchial Diseases
Immune System Diseases
Asthma
Rhinitis
Nose Diseases
Lung Diseases, Obstructive

Hypersensitivity
Respiratory Tract Diseases
Respiratory Tract Infections
Lung Diseases
Hypersensitivity, Immediate
Respiratory Hypersensitivity

ClinicalTrials.gov processed this record on May 06, 2009