Cardiovascular and Metabolic Responses to a Mixed Meal

This study is currently recruiting participants.

Verified by University of Missouri-Columbia, April 2009

First Received: April 14, 2009 Last Updated: April 16, 2009 History of Changes

Sponsored by:	University of Missouri-Columbia
Information provided by:	University of Missouri-Columbia
ClinicalTrials.gov Identifier:	NCT00882986

Purpose

The purpose is to determine whether regular endurance exercise and/or body weight influence the way our nervous and vascular systems respond during the metabolism of meals.

Condition
Insulin Resistance

MedlinePlus related topics: Exercise and Physical Fitness

U.S. FDA Resources

Study Type:	Observational
Study Design:	Case Control, Cross-Sectional
Official Title:	Role of Exercise Training and Body Weight on Cardiovascular and Metabolic Responses to a Mixed Meal Tolerance Test

Further study details as provided by University of Missouri-Columbia:

Primary Outcome Measures:

insulin/glucose response to mixed meal ingestion [ Time Frame: This study is cross-sectional. Primary and secondary measures will be assessed at a single timepoint. ] [ Designated as safety issue: No ]

Secondary Outcome Measures:

MSNA [ Time Frame: This is a cross-sectional study. Primary and seconardy measures will be assessed at a single visit lasting 4-6 hours. ] [ Designated as safety issue: No ]
Blood flow [ Time Frame: This is a cross-sectional study. Primary and seconardy measures will be assessed at a single visit lasting 4-6 hours. ] [ Designated as safety issue: No ]

Biospecimen Retention: None Retained

Biospecimen Description:

Estimated Enrollment:	60
Study Start Date:	January 2009
Estimated Study Completion Date:	December 2010
Estimated Primary Completion Date:	December 2010 (Final data collection date for primary outcome measure)

Groups/Cohorts
1 fit
2 unfit

Eligibility

Ages Eligible for Study:	20 Years to 50 Years
Genders Eligible for Study:	Male
Accepts Healthy Volunteers:	Yes
Sampling Method:	Non-Probability Sample

Study Population

young, lean, healthy men

Criteria

Inclusion Criteria:

healthy, not currently taking any medications

Exclusion Criteria:

unhealthy, taking medications

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00882986

Contacts

Contact: John P Thyfault, PhD

573-882-9818

Thyfaultj@missouri.edu

Locations

United States, Missouri
University of Missouri	Recruiting
Columbia, Missouri, United States, 65201
Contact: John P Thyfault, PhD 573-882-9818 Thyfaultj@missouri.edu

Sponsors and Collaborators

University of Missouri-Columbia

Investigators

Principal Investigator:

John P Thyfault, PhD

University of Missouri-Columbia

More Information

No publications provided

Responsible Party:	University of Missouri-Columbia ( Dr. John P. Thyfault Exercise Physiologist )
Study ID Numbers:	1121717
Study First Received:	April 14, 2009
Last Updated:	April 16, 2009
ClinicalTrials.gov Identifier:	NCT00882986 History of Changes
Health Authority:	United States: Institutional Review Board

Keywords provided by University of Missouri-Columbia:

insulin resistance

Study placed in the following topic categories:

Body Weight
Hyperinsulinism
Metabolic Diseases
Insulin Resistance

Glucose Metabolism Disorders
Metabolic Disorder
Insulin

Additional relevant MeSH terms:

Hyperinsulinism
Metabolic Diseases
Insulin Resistance
Glucose Metabolism Disorders

ClinicalTrials.gov processed this record on May 06, 2009