The Specific Lung Elastance in ALI/ARDS Patients in Supine and Prone Position

This study is currently recruiting participants.

Verified by Policlinico Hospital, September 2008

First Received: December 5, 2007 Last Updated: September 24, 2008 History of Changes

Sponsored by:	Policlinico Hospital
Information provided by:	Policlinico Hospital
ClinicalTrials.gov Identifier:	NCT00568659

Purpose

The investigators aim to study the specific lung elastance in ALI/ARDS patients during invasive mechanical ventilation, in supine and prone position.

Condition	Intervention
Acute Lung Injury Acute Respiratory Distress Syndrome	Procedure: specific elastance

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment, Non-Randomized, Open Label, Placebo Control, Single Group Assignment, Safety Study
Official Title:	The Specific Lung Elastance in ALI/ARDS Patients in Supine and Prone Position

Further study details as provided by Policlinico Hospital:

Primary Outcome Measures:

Specific elastance [ Time Frame: 5 minutes ] [ Designated as safety issue: No ]

Estimated Enrollment:	15
Study Start Date:	December 2007
Estimated Study Completion Date:	November 2008
Estimated Primary Completion Date:	November 2008 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
1: Experimental	Procedure: specific elastance The investigators study the specific lung elastance in ALI/ARDS patients in supine and prone position.

Detailed Description:

In sedated and paralyzed ALI/ARDS patients, we study and compare the specific lung elastance in supine and prone position during invasive mechanical ventilation.

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

ALI/ARDS patients during invasive mechanical ventilation

Exclusion Criteria:

Haemodynamic failure, pneumothorax

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00568659

Contacts

Contact: Davide Chiumello, MD

+39-0255033237

chiumello@libero.it

Locations

Italy
Policlinico Hospital	Recruiting
Milano, Italy, 20122
Contact: Davide Chiumello, MD +39-0255033237 chiumello@libero.it

Sponsors and Collaborators

Policlinico Hospital

Investigators

Principal Investigator:

Davide Chiumello, MD

Policlinico Hospital

More Information

No publications provided

Responsible Party:	Policlinico Hospital ( Chiumello Davide, MD )
Study ID Numbers:	1111
Study First Received:	December 5, 2007
Last Updated:	September 24, 2008
ClinicalTrials.gov Identifier:	NCT00568659 History of Changes
Health Authority:	Italy: National Monitoring Centre for Clinical Trials - Ministry of Health

Keywords provided by Policlinico Hospital:

Gas exchange
Respiratory mechanics
Ventilator Induced Lung Injury

Study placed in the following topic categories:

Respiratory Tract Diseases
Lung Diseases
Respiration Disorders

Respiratory Distress Syndrome, Adult
Acute Respiratory Distress Syndrome
Flatulence

Additional relevant MeSH terms:

Pathologic Processes
Disease
Respiratory Tract Diseases
Lung Diseases

Syndrome
Respiration Disorders
Respiratory Distress Syndrome, Adult

ClinicalTrials.gov processed this record on May 06, 2009