Acute Comfort and Blur of Systane and Optive

This study has been completed.

First Received: December 5, 2007 No Changes Posted

Sponsored by:	Alcon Research
Information provided by:	Alcon Research
ClinicalTrials.gov Identifier:	NCT00568386

Purpose

To evaluate drop comfort, acceptability, preference and blur profile between two marketed artificial tears in both dry eye and non-dry eye patient population.

Condition	Intervention
Dry Eye	Other: Systane Lubricant Eye Drops, Optive Lubricant Eye Drops

Drug Information available for: Tetrahydrozoline Tetrahydrozoline hydrochloride

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment, Randomized, Double-Blind, Active Control, Crossover Assignment
Official Title:	Acute Comfort and Blurring Profile Evaluation Comparing Systane Lubricant Eye Drops to Optive Lubricant Eye Drops

Further study details as provided by Alcon Research:

Primary Outcome Measures:

Drop comfort upon instillation, overall acceptability, three-minute visual blur profile [ Time Frame: 3 minutes ] [ Designated as safety issue: No ]

Enrollment:	40
Study Start Date:	November 2007
Study Completion Date:	December 2007

Intervention Details:

Eye Drop

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

Healthy, normal eyes OR documented diagnosis of dry eye

Exclusion Criteria:

Must not have worn contact lenses for 7 days preceding enrollment

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00568386

Locations

United States, Texas
Fort Worth
Fort Worth, Texas, United States, 76134

Sponsors and Collaborators

Alcon Research

Investigators

Principal Investigator:

Mike Christensen

Alcon Research

More Information

No publications provided

Responsible Party:	Alcon ( Mike Christensen )
Study ID Numbers:	M-07-02
Study First Received:	December 5, 2007
Last Updated:	December 5, 2007
ClinicalTrials.gov Identifier:	NCT00568386 History of Changes
Health Authority:	United States: Institutional Review Board

Keywords provided by Alcon Research:

Dry eye

Study placed in the following topic categories:

Pseudoephedrine
Oxymetazoline
Phenylephrine
Vasoconstrictor Agents
Ephedrine

Cardiovascular Agents
Peripheral Nervous System Agents
Tetrahydrozoline
Nasal Decongestants

Additional relevant MeSH terms:

Respiratory System Agents
Autonomic Agents
Sympathomimetics
Therapeutic Uses
Physiological Effects of Drugs
Vasoconstrictor Agents

Cardiovascular Agents
Peripheral Nervous System Agents
Tetrahydrozoline
Pharmacologic Actions
Nasal Decongestants

ClinicalTrials.gov processed this record on May 06, 2009