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Sponsored by: |
National Institute of Environmental Health Sciences (NIEHS) |
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Information provided by: | National Institute of Environmental Health Sciences (NIEHS) |
ClinicalTrials.gov Identifier: | NCT00013819 |
This is a study of the effects that lead has on the health of the central nervous system (for example, memory), peripheral nervous system (for example, sensation and strength in the hands and fingers), kidneys, blood pressure, and the blood forming system. A total of 803 lead workers and 135 persons without occupational lead exposure are being studied in South Korea. Lead in the body is being assessed by measurement of blood lead, chelatable lead (an estimate of lead in the tissues), and lead in bone. Subjects are tested three times each over three years. Several genetic factors are also being assessed for the role they play in the health effects of lead. These genes are known to differ among individuals. We are interested to know whether different forms of the same genes can modify the effect lead has on health.
Condition |
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Lead Poisoning |
Study Type: | Observational |
Study Design: | Natural History, Longitudinal, Defined Population, Prospective Study |
Ages Eligible for Study: | 17 Years to 70 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | Yes |
Lead workers in South Korea in one of 26 specific lead-using facilities.
Population controls in South Korea.
Study ID Numbers: | 7198-CP-001 |
Study First Received: | March 29, 2001 |
Last Updated: | June 23, 2005 |
ClinicalTrials.gov Identifier: | NCT00013819 History of Changes |
Health Authority: | United States: Federal Government |
lead poisoning central nervous system peripheral nervous system occupational health genetic susceptibility |
Disease Susceptibility Lead Poisoning Poisoning Disorders of Environmental Origin Genetic Predisposition to Disease |
Poisoning Lead Poisoning Disorders of Environmental Origin |