Study of Admission Versus Discharge After Transient Ischemic Attack (TIA)

This study is ongoing, but not recruiting participants.

First Received: March 16, 2006 Last Updated: March 30, 2007 History of Changes

Sponsored by:	University of California, San Diego
Information provided by:	University of California, San Diego
ClinicalTrials.gov Identifier:	NCT00304798

Purpose

Evaluate for difference in outcome between hospital admission versus discharge after recent TIA, and evaluate feasibility of a larger study.

Condition	Intervention	Phase
Transient Ischemic Attack (TIA) Stroke	Behavioral: Hospital admission	Phase I

MedlinePlus related topics: Transient Ischemic Attack

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment, Randomized, Open Label, Placebo Control, Parallel Assignment, Safety/Efficacy Study
Official Title:	Pilot Study of Admission Versus Discharge After Transient Ischemic Attack (TIA)

Further study details as provided by University of California, San Diego:

Primary Outcome Measures:

modified Rankin Scale at one year.

Secondary Outcome Measures:

Stroke and TIA incidence at one year, amount and cost of tests, adverse events.

Estimated Enrollment:	20
Study Start Date:	March 2006
Estimated Study Completion Date:	March 2007

Detailed Description:

20 patients will be randomized within 24 hours of a TIA to be admitted to the hospital or discharged to home, and we will compare outcomes, cost, and evaluate the feasibility of a larger study.

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Age 18 and older.
Clinical diagnosis of TIA within 24 hours of consent.

Exclusion Criteria:

Crescendo TIAs, defined as multiple within 24 hours of presentation.
Posterior circulation TIAs diagnosed clinically by a member of the Stroke Team.
High grade carotid stenosis.
Any compelling medical reason they should or should not be admitted or discharged (for example decompensated congestive heart failure, unstable angina, new EKG changes, pneumonia, sepsis). Patients will only be enrolled if the only consideration for admission is the TIA, and they otherwise meet appropriate standard of care criteria for discharge to home.
Patients will be excluded if no one can be with them for the next 12 hours to ensure a rapid call to 911 should problems arise, specifically stroke.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00304798

Locations

United States, California
UCSD
San Diego, California, United States, 92103

Sponsors and Collaborators

University of California, San Diego

Investigators

Principal Investigator:

Matt B Jensen, MD

UCSD Stroke Center

More Information

No publications provided

Study ID Numbers:	UCSD IRB #051272
Study First Received:	March 16, 2006
Last Updated:	March 30, 2007
ClinicalTrials.gov Identifier:	NCT00304798 History of Changes
Health Authority:	United States: Institutional Review Board

Keywords provided by University of California, San Diego:

Transient Ischemic Attack (TIA).
Stroke.
Hospital admission.

Study placed in the following topic categories:

Ischemic Attack, Transient
Cerebral Infarction
Stroke
Vascular Diseases
Central Nervous System Diseases

Brain Ischemia
Ischemia
Brain Diseases
Cerebrovascular Disorders

Additional relevant MeSH terms:

Ischemic Attack, Transient
Pathologic Processes
Nervous System Diseases
Stroke
Vascular Diseases
Central Nervous System Diseases

Brain Ischemia
Cardiovascular Diseases
Ischemia
Brain Diseases
Cerebrovascular Disorders

ClinicalTrials.gov processed this record on May 06, 2009