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| Sponsored by: |
University of Aarhus |
|---|---|
| Information provided by: | University of Aarhus |
| ClinicalTrials.gov Identifier: | NCT00820729 |
Purpose
The presence of an abnormally increased pulmonary blood pressure worsens the prognosis of patients with interstitial pulmonary disease.
The aim of this study is to estimate the frequency of an increased blood pressure in the lungs among patient with interstitial pulmonary disease, and to evaluate the use of different biomarkers in diagnosis of the condition.
| Condition |
|---|
|
Interstitial Lung Disease Pulmonary Hypertension Biomarkers |
| Study Type: | Observational |
| Study Design: | Cohort, Cross-Sectional |
| Official Title: | The Prevalence of Pulmonary Hypertension and the Significance of Different Biomarkers in Chronic Interstitial Pulmonary Disease |
blood samples
| Estimated Enrollment: | 200 |
| Study Start Date: | March 2009 |
| Estimated Study Completion Date: | December 2011 |
| Estimated Primary Completion Date: | December 2011 (Final data collection date for primary outcome measure) |
| Groups/Cohorts |
|---|
|
1
Patients with interstitial pulmonary disease
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The presence of increased pulmonary blood pressure is established by echocardiography and confirmed by right heart catheterization.
The ability of NT-proBNP, vWf, troponin-t, D-dimer and exhaled NO to predict the presence of increased pressure in the pulmonary circulation is evaluated.
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Probability Sample |
Out-patients with interstitial pulmonary disease.
Inclusion Criteria: - Interstitial pulmonary disease
Contacts and Locations| Contact: Charlotte Andersen, MD | 00 45 89 42 17 91 | cua@farm.au.dk |
| Contact: Ole Hilberg, MDsc | oh@mil.au.dk |
| Denmark | |
| Department of Pulmonary Diseases, Århus Sygehus | |
| Århus, Denmark, Dk-8000 | |
| Department of Cardiology, Skejby sygehus | |
| Århus N, Denmark, DK-8200 | |
More Information
| Responsible Party: | Århus University Hospital ( Elisabeth Bendstrup ) |
| Study ID Numbers: | Fibrosis-ECHO 2009 |
| Study First Received: | January 9, 2009 |
| Last Updated: | January 9, 2009 |
| ClinicalTrials.gov Identifier: | NCT00820729 History of Changes |
| Health Authority: | Denmark: Ethics Committee |
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interstitial lung disease pulmonary hypertension biomarkers NT-pro-BNP |
von Willebrand factor D-dimer Exhaled NO Troponin-t |
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Von Willebrand Disease Lung Diseases, Interstitial Respiratory Tract Diseases Hypertension, Pulmonary |
Lung Diseases Vascular Diseases Fibrin fragment D Hypertension |
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Lung Diseases, Interstitial Respiratory Tract Diseases Hypertension, Pulmonary Lung Diseases |
Vascular Diseases Cardiovascular Diseases Hypertension |
