Smoking Reduction Intervention for Smokers Not Willing to Quit Smoking: a Randomised Control Trial

This study is currently recruiting participants.

Verified by Hospital Authority, Hong Kong, June 2008

First Received: November 21, 2007 Last Updated: December 15, 2008 History of Changes

Sponsors and Collaborators:	Hospital Authority, Hong Kong Dept of Community Medicine, HKU
Information provided by:	Hospital Authority, Hong Kong
ClinicalTrials.gov Identifier:	NCT00563329

Purpose

The aims of this study are (1) to examine the effect of smoking reduction intervention (reduction counseling and nicotine replacement therapy, NRT) (a) on smoking cessation and (b) on reducing daily cigarette consumption among smokers not willing to quit smoking but want to reduce smoking, and (2) to examine the effect of adherence intervention in producing a higher (a) adherence rate, (b) reduction rate, and (c) quit rate.

Condition	Intervention
Smoking Cessation	Procedure: Reduction Intervention + Adherence Intervention Behavioral: Reduction Intervention Procedure: control

MedlinePlus related topics: Quitting Smoking Smoking

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Randomized, Single Blind, Placebo Control, Single Group Assignment, Efficacy Study
Official Title:	Smoking Reduction Intervention for Smokers Not Willing to Quit Smoking: a Randomised Control Trial

Further study details as provided by Hospital Authority, Hong Kong:

Primary Outcome Measures:

quit rate [ Time Frame: 6 months ]
Reduction Rate (reduction of cigarette consumption by at least 50% compared with baseline) [ Time Frame: 6 months ]
Adherence Rate to NRT [ Time Frame: 4 weeks ]

Secondary Outcome Measures:

Validated quit rate (by measuring exhaled CO and urinary cotinine level) [ Time Frame: 6 months ]
Quit rate without validation [ Time Frame: 1 month ]
self-reported use of NRT for at least 4 weeks or 8 weeks, without cotinine validation [ Time Frame: 1 month / 3 month ]

Estimated Enrollment:	3826
Study Start Date:	October 2004
Estimated Study Completion Date:	July 2006

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both

Criteria

Inclusion Criteria:

Age 18 or above
Ethnic Chinese male or female
Smokes at least 2 cigarettes per day
Have no intention to quit in the near future
Intends to reduce smoking in the next 7 days
Has no contraindication to NRT

Exclusion Criteria:

Subjects who are psychologically or physically unable to communicate
Children and teenagers (age below 18)
Pregnant or intention to become pregnant within the next 6 months
Those on regular psychotropic medications and in the presence of any serious health problems that may make them unsuitable for using NRT, such as recent stroke, palpitation, or other life threatening conditions

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00563329

Contacts

Contact: TH Lam, Prof

(852) 2819 9280

hrmrlth@hkucc.hku.hk

Locations

China
The University of Hong Kong	Recruiting
Hong Kong, China
Sub-Investigator: Sophia SC Chan, Dr
Sub-Investigator: Anthony J Hedley, Prof
Sub-Investigator: Abu SM Abdullah, Prof
HAHO	Recruiting
Hong Kong, China
Sub-Investigator: Vivian T Wong, Dr
Hong Kong Council on Smoking and Health	Recruiting
Hong Kong, China
Sub-Investigator: Alfred YW Chan, Mr

Sponsors and Collaborators

Hospital Authority, Hong Kong

Dept of Community Medicine, HKU

Investigators

Principal Investigator:

TH Lam, Prof

Department of Community Medicine, Faculty of Medicine, The University of Hong Kong

More Information

Additional Information:

HAREC Clinical Trial Registry This link exits the ClinicalTrials.gov site

No publications provided

Study ID Numbers:	UW 03-103 T/103, HARECCTR0500051
Study First Received:	November 21, 2007
Last Updated:	December 15, 2008
ClinicalTrials.gov Identifier:	NCT00563329 History of Changes
Health Authority:	Hong Kong: Ethics Committee

Keywords provided by Hospital Authority, Hong Kong:

Smokers who are not willing to quit in the near future but intend to reduce smoking

Study placed in the following topic categories:

Smoking

Additional relevant MeSH terms:

Habits
Smoking

ClinicalTrials.gov processed this record on May 06, 2009