What Are the Signs and Symptoms of
Hemochromatosis?
Hemochromatosis can affect many parts of the body
and can cause various signs and symptoms. Many of the signs and symptoms are
similar to those of other diseases. As many as half of the people who have
hemochromatosis may not have signs or symptoms.
Signs and symptoms of hemochromatosis usually don't
occur until middle age. Women are more likely to have general symptoms first,
such as fatigue (tiredness). In men, complications such as
diabetes or cirrhosis (scarring of the liver) often are the
first sign of the disease.
Signs and symptoms also vary based on how severe the
disease is. Common signs and symptoms of hemochromatosis include joint pain,
fatigue, general weakness, weight loss, and abdominal pain.
Hemochromatosis Complications
If hemochromatosis isn't found and treated early,
iron builds up in your body and can lead to:
- Liver disease, including an enlarged liver, liver
failure, liver cancer, or cirrhosis (scarring of the liver)
- Heart problems, including
arrhythmias
(irregular heartbeats) and
heart
failure
- Diabetes, especially in people who have a family
history of diabetes
- Joint damage and pain, including arthritis
- Reproductive organ failure, such as impotence,
shrinkage of the testicles, and loss of sex drive in men, and absence of the
menstrual cycle and early menopause in women
- Changes in skin color that make the skin look
gray or bronze
- Underactive pituitary and thyroid glands
- Damage to the adrenal glands
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