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| 2.5 billion people in tropical areas of the world are at risk for dengue infection. In the Americas, dengue hemorrhagic fever is on the rise: the mean annual number of reported cases in the Americas between 1989 and 1993 increased over 50-fold, as compared with the preceding 5-year period, from 1984 to 1988. With the widespread abundance of Aedes aegypti in the Americas, there is danger that this worsening trend will continue, unless we improve disease control efforts. |
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