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Award Abstract #0353569
REU Site in Biomolecular Engineering


NSF Org: EEC
Division of Engineering Education and Centers
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Initial Amendment Date: May 6, 2004
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Latest Amendment Date: July 17, 2006
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Award Number: 0353569
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Award Instrument: Continuing grant
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Program Manager: Esther Bolding
EEC Division of Engineering Education and Centers
ENG Directorate for Engineering
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Start Date: June 1, 2004
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Expires: May 31, 2008 (Estimated)
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Awarded Amount to Date: $325544
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Investigator(s): Andrew Zydney zydney@engr.psu.edu (Principal Investigator)
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Sponsor: Pennsylvania State Univ University Park
110 Technology Center Building
UNIVERSITY PARK, PA 16802 814/865-1372
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NSF Program(s): HUMAN RESOURCES DEVELOPMENT
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Field Application(s):
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Program Reference Code(s): SMET, 9250, 9178
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Program Element Code(s): 1360

ABSTRACT

This award provides support for a three-year REU Site at the Pennsylvania State University, University Park campus. Twelve students will be recruited from throughout the U.S. for a ten-week summer experience in research related to biomolecular engineering. Students will have an opportunity to do research aimed at understanding the engineering challenges involved in the production, purification, and application of biological molecules. REU participants will work closely with faculty, graduate students, and post-docs on cutting-edge projects ranging from developing membrane systems for protein purification, to understanding intermolecular forces involved in bacterial adhesion, to developing nanoparticles for drug delivery, to optimizing directed evolution protocols for novel engineered proteins, to the synthesis of monoclonal antibodies in transgenic plants. The program will provide opportunities for student participants to learn how to effectively communicate their research results through a poster session held at the end of the summer. This program will provide a unique opportunity for undergraduate students to gain a broad exposure to the field of biomolecular engineering and will provide a unique opportunity for students majoring in fields such as biochemistry and molecular biology to gain an engineering perspective on this research field. It is anticipated that this program will have a Broader Impact on the nations need to increase the number of U.S. citizens and permanent residents engaged in research-related careers at U.S. universities, government agencies, and in private-sector organizations. It is also anticipated that this REU Site will have a Broader Impact on the nations need to have broader participation in the research enterprise of citizens and permanent residents from demographic groups traditionally underrepresented in science and engineering.


PUBLICATIONS PRODUCED AS A RESULT OF THIS RESEARCH

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Andrews, L. B., and Curtis, W.R..  "Comparison of transient expression in tobacco leaves and plant suspension culture,"  Biotechnology Progress,  v.21,  2005,  p. 946.

Dorfman, A., N. Kumar, J. Hahm.  "Nanoscale ZnO-enhanced Fluorescence Detection of Protein Interactions,"  Advanced Materials,  v.18,  2006,  p. 2685.

Dorfman, A., N. Kumar, J. Hahm.  "Highly Sensitive Biomolecular Fluorescence Detection using Nanoscale ZnO Platforms,"  Langmuir,  v.22,  2006,  p. 4890.

Kumar, N., A. Dorfman, and J. Hahm.  "Fabrication of optically enhanced ZnO nanorods and microrods using novel biocatalysts,"  Journal of Nanoscience and Nanotechnology,  v.5,  2005,  p. 1915.

Kumar, N., A. Dorfman, J. Hahm.  "Ultrasensitive DNA Sequence Detection of Bacillus anthracis using Nanoscale ZnO Sensor Arrays,"  Nanotechnology,  v.17,  2006,  p. 2875.

Kumar, N; Parajuli, O; Dorfman, A; Kipp, D; Hahm, JI.  "Activity study of self-assembled proteins on nanoscale diblock copolymer templates,"  LANGMUIR,  v.23,  2007,  p. 7416 - 7422.  

Latulippe, D. R., K. Ager, and A. L. Zydney.  "Flux dependent transmission of supercoiled plasmid DNA through ultrafiltration membranes,"  Journal of Membrane Science,  v.294,  2007,  p. 169.

Nair, S; Kim, J; Crawford, B; Kim, SH.  "Improving biocatalytic activity of enzyme-loaded nanofibers by dispersing entangled nanofiber structure,"  BIOMACROMOLECULES,  v.8,  2007,  p. 1266 - 1270.  

Pantazes, RJ; Saraf, MC; Maranas, CD.  "Optimal protein library design using recombination or point mutations based on sequence-based scoring functions,"  PROTEIN ENGINEERING DESIGN & SELECTION,  v.20,  2007,  p. 361 - 373.  

Parajuli, O; Kumar, N; Kipp, D; Hahm, JI.  "Carbon nanotube cantilevers on self-aligned copper silicide nanobeams,"  APPLIED PHYSICS LETTERS,  v.90,  2007,   

Salerno, M.B., Rothstein, S.,, Nwachukwu, C., Shelbi, H., Velegol, D., and Logan, B.E.  "Differences between chemisorbed and physisorbed biomolecules on particle deposition to hydrophobic surfaces,"  Environmental Science and Technology,  v.39,  2005,  p. 6371.

Velegol D., Holtzer G.L., Radovic-Moreno A.F., and Cuppett, J.D.,.  "Force measurements between sub-100 nm colloidal particles,"  Langmuir,  v.23,  2007,  p. 1275.

Yake A.M., Panella R.A., Snyder C.E., and Velegol, D.,.  "Fabrication of colloidal doublets by a salting out-quenching-fusing technique,"  Langmuir,  v.22,  2006,  p. 9135.


(Showing: 1 - 13 of 13).

 

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Last Updated:April 2, 2007