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Applying a mixed-integer program to model re-screening
women who test positive for C. trachomatis infection.
Health Care Management Science 2004;7(2):135-144.
Tao G, Abban BK, Gift TL, Chen G, Irwin KL.
Abstract
We proposed a mixed-integer program to model the management of C. trachomatis
infections in women visiting publicly funded family planning clinics. We
intended to maximize the number of infected women cured of C. trachomatis
infections. The model incorporated screening, re-screening, and treatment
options for three age groups with respective age-specific C. trachomatis
infection and re-infection rates, two possible test assays, and two possible
treatments. Our results showed the total budget had a great impact on the
optimal strategy incorporating screening coverage, test selection, and treatment.
At any budget level, the strategy that used a relatively small per-patient
budget increase to re-screen all women who tested positive 6 months earlier
always resulted in curing more infected women and more cost-saving than the
strategy that was optimal under the condition of not including a re-screening
option.