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NIGMS-funded researchers have been able to follow the changing shape of individual alpha-synuclein proteins, which are linked to Parkinson's and Alzheimer's diseases.
NIGMS-supported researchers are the first to observe the dynamic, ratchet-like movements of single ribosomal molecules in the act of building proteins from genetic blueprints.
NIGMS-supported researchers have developed a method using optical tweezers to better understand how DNA-drug interactions occur.
An NIGMS-funded study used single-molecule fluorescent imaging to trace the role of reverse transcriptase in real time.