NIDA Research Monograph, Number 138 [Printed in 1994]
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Download Monograph138.pdf - Imaging Techniques in Medications Development:
Preclinical and Clinical Aspects (1.7 MB)
Table of Contents
PET, SPECT, and Probes in Drug Design and Development-----1
Henry N. Wagner, Jr.
Positron Emission Tomography in Studies of Drug Abuse-----15
Edythe D. London
Imaging Brain Function in Animals To Understand Drugs of Abuse and Potential Pharmacotherapies-----25
M.F. Piercey
Brain-Imaging Studies of the Combined Use of Cocaine and Alcohol and of the Pharmacokinetics of Cocaethylene-----41
Nora D. Volkow and Joanna S. Fowler
Positron Emission Tomography of Cocaine Binding Sites on the Dopamine Transporter-----57
Bertha K. Madras, David R. Elmaleh, Peter C. Meltzer, Anna Y. Liang, Gordon L. Brownell, and Anna-Liisa Brownell
Metabolic Mapping Methods for the Identification of the Neural Substrates of the Effects of Novel Tropane Analogs-----71
Linda J. Porrinno, Lisa Williams-Hemby, and Huw M.L. Davies
Noninvasive Evaluation of the Sympathetic Nervous System of the Heart by Nuclear Imaging Procedures-----85
Markus Schwaiger, James C. Sisson, and Donald Wieland
Development of PET/SPECT Ligands for the Serotonin Transporter-----111
Ursula Scheffel, Robert F. Dannals, Makiko Suehiro, George A. Ricaurte, F. Ivy Carroll, Michael J. Kuhar, and Henry N. Wagner, Jr.
SPECT Imaging of Dopamine and Serotonin Transporters in Nonhuman Primate Brain-----131
Marc Laruelle, Ronald M. Baldwin, and Robert B. Innis
Cerebra Blood Flow Changes With Acute Cocaine Intoxication: Clinical Correlations With SPECT, CT, and MRI-----161
I. Mena, R.J. Giornbetti, B.L. Miller, K. Garrett, J. Villanueva-Meyer, C. Mody, and M.A. Goldberg
An Introduction to Magnetic Resonance Methods for Clinical Research-----175
Gerald G. Blackwell
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