Agency for Toxic Substances and Disease Registry
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Learning Objectives |
Upon completion of this section, you should be able to
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Introduction |
There is no antidote for TCE poisoning. Treatment consists of support of respiratory and cardiovascular functions. |
Acute Exposure |
In the case of dermal contact with liquid TCE, contaminated clothes should be removed and the affected areas washed with copious amounts of soap and water. Direct eye splashes require irrigation for at least 15 minutes. Corneal epithelium damage usually resolves spontaneously after irrigation. Patients should be removed from the contaminated environment as soon as possible; begin artificial ventilation, if needed. Those with altered mental status or apparent respiratory insufficiency should receive supplemental oxygen. If the patient's pulse is absent, cardiopulmonary resuscitation should be initiated. Gut decontamination (emesis, lavage, or saline cathartic) is recommended if it can be initiated within two to three hours after the ingestion of more than a swallow of TCE. However, the effects of these measures have not been clinically evaluated. If emesis is considered, administer the emetic only to patients who are fully conscious and have an intact gag reflex. Activated charcoal has not been proven to absorb TCE, but, in general, it effectively decreases absorption of most ingested toxic agents.
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Chronic Exposure |
No known treatment for chronic exposure to TCE exists. Potentially involved organ systems should be independently evaluated, and supportive measures should be initiated. |
Key Points |
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Progress Check |