Primate Cortico-Basal Ganglia Network and Decision Making |
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| Launch in standalone player | |
| Air date: | Monday, March 30, 2009, 12:00:00 PM |
| Category: | Neuroscience |
| Description: | Decision making is ubiquitous, and the ability to develop the knowledge about the animal's environment from experience and use this knowledge to produce a series of actions that will maximize the overall reward is essential for survival. Dr. Lee's laboratory focuses on the role of the prefrontal cortex and the basal ganglia in evaluating the outcomes of the animal's previous choices and incorporating this information to improve the animal's decision-making strategies. His research is highly inter-disciplinary and capitalizes on the insights from formal theories of economics and reinforcement learning as well as computational neuroscience of neural coding and behavioral studies of decision making. His laboratory also develops novel behavioral paradigms that can probe the core processes of decision making. Combined with the use of a large-scale multi-electrode recording system, this research seeks to unravel the biological basis of willful actions.
Selected Publications: Behavioral and neural changes after gains and losses of conditioned reinforcers. Seo H, Lee D., J Neurosci. 2009 Mar 18;29(11):3627-41. Neural dissociation of delay and uncertainty in intertemporal choice. Luhmann CC, Chun MM, Yi DJ, Lee D, Wang XJ., J Neurosci. 2008 Dec 31;28(53):14459-66. Prefrontal coding of temporally discounted values during intertemporal choice. Kim S, Hwang J, Lee D., Neuron. 2008 Jul 10;59(1):161-72. Erratum in: Neuron. 2008 Aug 14;59(3):522. Game theory and neural basis of social decision making. Lee D., Nat Neurosci. 2008 Apr;11(4):404-9. Epub 2008 Mar 26. Review. Order-dependent modulation of directional signals in the supplementary and presupplementary motor areas. Sohn JW, Lee D., J Neurosci. 2007 Dec 12;27(50):13655-66. To touch or not to touch: posterior parietal cortex and voluntary behavior. Lee D., Neuron. 2007 Nov 8;56(3):419-21. For more information see our website - NIH Neuroscience Seminar Series |
| Author: | Daeyeol Lee, Ph.D., Department of Neurobiology, Yale University School of Medicine |
| Runtime: | 75 minutes |
| Download: | Download
Video How to download a Videocast |
| CIT File ID: | 15002 |
| CIT Live ID: | 7142 |
| Permanent link: | http://videocast.nih.gov/launch.asp?15002 |
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Enhanced Audio Podcast | 1:07:56 |
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Enhanced Video Podcast | 1:07:56 | |