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HIV/AIDS
 Understanding
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  How HIV Causes AIDS
  HIV Risk Factors
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HIV/AIDS

Symptoms

Early symptoms

Many people will not have any symptoms when they first become infected with HIV. They may, however, have a flu-like illness within a month or two after exposure to the virus. This illness may include

  • Fever
  • Headache
  • Tiredness
  • Enlarged lymph nodes (glands of the immune system easily felt in the neck and groin)

These symptoms usually disappear within a week to a month and are often mistaken for those of another viral infection. During this period, people are very infectious, and HIV is present in large quantities in genital fluids.

Later symptoms

More persistent or severe symptoms may not appear for 10 years or more after HIV first enters the body in adults, or within 2 years in children born with HIV infection. This period of asymptomatic infection varies greatly in each person. Some people may begin to have symptoms within a few months, while others may be symptom-free for more than 10 years.

Even during the asymptomatic period, the virus is actively multiplying, infecting and killing cells of the immune system. The virus can also hide within infected cells and be inactive. The most obvious effect of HIV infection is a decline in the number of CD4 positive T (CD4+) cells found in the blood—the immune system’s key infection fighters. The virus slowly disables or destroys these cells without causing symptoms.

As the immune system becomes more debilitated, a variety of complications start to take over. For many people, the first signs of infection are large lymph nodes, or swollen glands, that may be enlarged for more than 3 months. Other symptoms often experienced months to years before the onset of AIDS include

  • Lack of energy
  • Weight loss
  • Frequent fevers and sweats
  • Persistent or frequent yeast infections (oral or vaginal)
  • Persistent skin rashes or flaky skin
  • Pelvic inflammatory disease in women that does not respond to treatment
  • Short-term memory loss

Some people develop frequent and severe herpes infections that cause mouth, genital, or anal sores, or a painful nerve disease called shingles. Children may grow slowly or get sick frequently.

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Highlights

NIAID Media Availability: Well-Armed Immune Cells Help Long-Term Non-Progressors Contain HIV
Dec. 4, 2008

25 Years of HIV/AIDS Science: Reaching the Poor with Research Advances (Commentary published in Cell)
Nov. 2, 2007

Related Links

View a list of links for more information about HIV/AIDS.

See Also

  • Early, Consistent Treatment Could Help Eliminate HIV
  • MicroRNAs Help HIV Hide
  • HIV/AIDS News Releases
  • Selected NIAID Science Advances, 2007-2008 (PDF)
  • Understanding Sexually Transmitted Infections
  • See Also

  • Pelvic Inflammatory Disease
  • Shingles
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    Highlights

    NIAID Media Availability: Well-Armed Immune Cells Help Long-Term Non-Progressors Contain HIV
    Dec. 4, 2008

    25 Years of HIV/AIDS Science: Reaching the Poor with Research Advances (Commentary published in Cell)
    Nov. 2, 2007

    Related Links

    View a list of links for more information about HIV/AIDS.

    See Also

  • Early, Consistent Treatment Could Help Eliminate HIV
  • MicroRNAs Help HIV Hide
  • HIV/AIDS News Releases
  • Selected NIAID Science Advances, 2007-2008 (PDF)
  • Understanding Sexually Transmitted Infections
  • See Also

  • Pelvic Inflammatory Disease
  • Shingles