Molecular Detection and Staging of Cancer

 


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Air date: Wednesday, March 18, 2009, 2:30:00 PM
Category: Special
Runtime: 60 minutes
NLM Title: Molecular detection and staging of cancer [electronic resource] / David Sidransky.
Series: NIDCR 2009 seminar series
Author: Sidransky, David.
National Institutes of Health (U.S.)
Publisher: [Bethesda, Md. : National Institutes of Health, 2009]
Other Title(s): NIDCR 2009 seminar series
Abstract: (CIT): NIDCR 2009 Seminar Series: From Basic Research to Therapy -- The Latest Frontier Dr. David Sidransky of Johns Hopkins University will discuss his recent findings of genetic and epigenetic markers of lung and head and neck cancers, and will describe how genetic alterations can be used to predict the development and progression of these cancers. He will also talk about new xenograft models of human cancers and their use in drug development and personalization of cancer therapies, and the use of technologies to track new markers in these models and in clinical samples. A pioneer in the molecular detection of cancer, Dr. Sidransky was the first to show that oncogenes and tumor suppressor gene mutations could be detected in urine, stool, and sputum from bladder, colon, and lung cancer patients, respectively. He has also shown that such mutations can be detected in surgical margins and lymph nodes, providing information about the spread of disease that cannot be obtained through standard pathologic examination. Dr. Sidransky is a Professor of Otolaryngology, Oncology, Pathology, Urology, Genetics, and Cellular and Molecular Medicine at Johns Hopkins University (JHU). He is also the director of head and neck cancer research at the JHU Kimmel Comprehensive Cancer Center as well as a principal investigator at JHU's Head and Neck Cancer SPORE, or Specialized Program of Research Excellence. For more information, visit http://www.nidcr.nih.gov/NewsAndFeatures/Announcements/NewSeminarSeries.htm.
Subjects: Molecular Diagnostic Techniques
Neoplasm Staging
Neoplasms--diagnosis
Neoplasms--genetics
Neoplasms--pathology
Publication Types: Government Publications
Lectures
NLM Classification: QZ 241
NLM ID: 101501606
CIT File ID: 14977
CIT Live ID: 7553
Permanent link: http://videocast.nih.gov/launch.asp?14977