Induction & Regulation of Th17-dependent Airway Hyperresponsiveness

 


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Air date: Wednesday, March 11, 2009, 4:15:00 PM
Category: Immunology
Description: One of NIH's own, Don Cook has made truly pioneering contributions to immunology, including the first chemokine knockout mouse (CCL3), which he used to show for the first time that chemokines regulate viral immunopathogenesis (both Coxsacckie virus myocarditis and influenza virus pneumonia); and the CCR6 knockout mouse, which he used to provide the first evidence that chemokines are critically involved in mucosal immunology. His current work is focused on the molecular and cellular mechanisms underlying allergic sensitization and immunotolerance to inhaled antigens, with the ultimate goal of improving therapies for patients. These studies include the analysis of dendritic cell subsets in the lung, toll-like receptors, cytokines, chemoattractants, and analysis of the impact of route of sensitization and adjuvant on allergic sensitization. Don does important work and is an engaging speaker. His IIG seminar is one you will NOT want to miss.

http://www.niehs.nih.gov/research/atniehs/labs/lrb/immuno-gen/index.cfm

For more information, visit
The Immunology Interest Group
Author: Donald Cook
Runtime: 75 minutes
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CIT File ID: 14963
CIT Live ID: 7451
Permanent link: http://videocast.nih.gov/launch.asp?14963