DAVID Bioinformatics
The Database for Annotation, Visualization and Integrated Discovery
Functional Annotation Tool
DAVID Bioinformatics Resources 2008, NIAID/NIH
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  • AFFYMETRIX
    • Canine
    • HC-G110
    • HG-Focus
    • HG-U133A
    • HG-U133B
    • HG-U133_Plus_2
    • HG-U95Av2
    • HG-U95B
    • HG-U95C
    • HG-U95D
    • HG-U95E
    • Hu35KsubA
    • Hu35KsubB
    • Hu35KsubC
    • Hu35KsubD
    • HuGene-1_0-st-v1
    • HuGeneFl
    • MG-U74Av2
    • MG-U74Bv2
    • MG-U74Cv2
    • MOE430A
    • MOE430B
    • Mouse430_2
    • RAE230A
    • RAE230B
    • RG_U34A
    • RG_U34B
    • RG_U34C
    • Rat230_2
    • U133_X3P Array
  • ILLUMINA
    • HUMANHT-12_V3_0_R1_11283641_A
    • HUMANREF-8_V2_0_R3_11223162_A
    • HUMANREF-8_V3_0_R1_11282963_A
    • HUMANWG-6_V2_0_R3_11223189_A
    • HUMANWG-6_V3_0_R1_11282955_A
    • MOUSEREF-8_V1_1_R3_11234312_A
    • MOUSEREF-8_V2_0_R1_11278551_A
    • MOUSEWG-6_V1_1_R3_11234304_A
    • MOUSEWG-6_V2_0_R1_11278593_A
    • RATREF-12_V1_0_R3_11222119_A
    
Bioinformatic Resources
Functional Annotation Tool

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Key Concepts:

The DAVID Gene Concept
DAVID 2.0 is design around the "DAVID Gene Concept", a graph theory evidence-based method to agglomerate species-specific gene/protein identifiers from a variety of public genomic resources including NCBI, PIR and Uniprot/SwissProt. The DAVID Gene Concept method groups tens of million of identifiers from over 65,000 species into 1.5 million unique protein/gene records. More
 
Term/Gene Co-Occurrence Probability
Ranking functional categories based on co-occurrence with sets of genes in a gene list can rapidly aid in unraveling new biological processes associated with cellular functions and pathways. DAVID 2.0 allows investigators to sort gene categories from dozens of annotation systems. Sorting can be based either the number of genes within each category or by the EASE-score. More
 
Gene Similarity Search
Any given gene is associating with a set of annotation terms. If genes share similar set of those terms, they are most likely involved in similar biological mechanisms. The algorithm tries to group those related genes based on the agreement of sharing similar annotation terms by Kappa statistics. More
 
Term Similarity Search
Typically, a biological process/term is done by a corporation of a set of genes. If two or more biological processes are done by similar set of genes, the processes might be related in the biological network somehow. This search function is to identify the related biological processes/terms by quantitatively measuring the degree of the agreement how terms share the similar participating genes. More
 Integrated Solutions
  Functional Annotation

 

  Numerous Data Sources
  Co-occurrence Probability
  Use Homolog Annotation
  Dynamic Pathway Maps
  Disease Associations

 





 Please cite the web site or Genome Biology 2003; 4(5):P3 within any publication that makes use of any methods inspired by DAVID.
                          

        

                 
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