Antigen Presenting Cell Dysregulation as a Mechanism Underlying Immune Evasion by Helminth Parasites |
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Launch in standalone player | |
Air date: | Wednesday, May 06, 2009, 4:15:00 PM |
Category: | Immunology |
Description: | The interests of Roshanak Tolouei Semnani have revolved around dendritic cells and their role in directing specific T cell responses. As a graduate student at the University of Chicago, her work involved the role of co-stimulatory molecules in the T cell differentiation and activation process. Since coming to the NIH, her work has focused on the host parasite interface. She has established the importance of dendritic cell dysfunction in mediating the profound T cell hyporesponsiveness seen in parasitic helminth infection and has helped define many of the underlying mechanisms involved in this alteration of APC dysfunction. She has clearly defined novel mechansims by which parasitic human pathogens evade the host immune response thereby ensuring their continued survival and longevity. Originally from Iran, Roshanak is currently a Staff Scientist in the Laboratory of Parasitic Diseases (LPD). She has already received many local awards for her work on human dendritic cells as well as several "mentoring" awards for her guidance of students in the LPD.
For more information, visit The Immunology Interest Group |
Author: | Dr. Roshanak Tolouei Semnani, Staff Scientist, NIAID, Helminth Immunology Section |
Runtime: | 75 minutes |
Download: | Download
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CIT File ID: | 15090 |
CIT Live ID: | 7458 |
Permanent link: | http://videocast.nih.gov/launch.asp?15090 |