1. Hajduch J, Nam G, Kim EJ, Frohlich R, Hanover JA, Kirk KL A convenient synthesis of the C-1-phosphonate analogue of UDP-GlcNAc and its evaluation as an inhibitor of O-linked GlcNAc transferase (OGT). Carbohydr Res, 2007. [Full Text/Abstract]
2. Wesierska-Gadek J, Klima A, Ranftler C, Komina O, Hanover J, Invernizzi P, Penner E. Characterization of the antibodies to p62 nucleoporin in primary biliary cirrhosis using human recombinant antigen. J Cell Biochem, 2007. [Full Text/Abstract]
3. Kim EJ, Amorelli B, Abdo M, Thomas CJ, Love DC, Knapp S, Hanover JA Distinctive Inhibition of O-GlcNAcase Isoforms by an alpha-GlcNAc Thiolsulfonate. J Am Chem Soc, 2007. [Full Text/Abstract]
4. Kim CS, Furuya F, Ying H, Kato Y, Hanover JA, Cheng SY Gelsolin: a novel thyroid hormone receptor-beta interacting protein that modulates tumor progression in a mouse model of follicular thyroid cancer. Endocrinology(148): 1306-12, 2007. [Full Text/Abstract]
5. Furuya F, Guigon CJ, Zhao L, Lu C, Hanover JA, Cheng SY Nuclear receptor corepressor is a novel regulator of phosphatidylinositol 3-kinase signaling. Mol Cell Biol(27): 6116-26, 2007. [Full Text/Abstract]
6. Knapp S, Abdo M, Ajayi K, Huhn RA, Emge TJ, Kim EJ, Hanover JA Tautomeric modification of GlcNAc-thiazoline. Org Lett(9): 2321-4, 2007. [Full Text/Abstract]
7. Hanover JA, Love DC, Deangelis N, O''Kane ME, Lima-Miranda R, Schulz T, Yen YM, Johnson RC, Prinz WA The High Mobility Group Box Transcription Factor Nhp6Ap Enters the Nucleus by a Calmodulin-dependent, Ran-independent Pathway. J Biol Chem(282): 33743-51, 2007. [Full Text/Abstract]
8. Zhao Y, Conze DB, Hanover JA, Ashwell JD Tumor necrosis factor receptor 2 (TNFR2) signaling induces selective c-IAP1-dependent ASK1 ubiquitination and terminates MAP kinase signaling. J Biol Chem , 2007. [Full Text/Abstract]
9. Ying H, Furuya F, Zhao L, Araki O, West BL, Hanover JA, Willingham MC, Cheng SY Aberrant accumulation of PTTG1 induced by a mutated thyroid hormone beta receptor inhibits mitotic progression. J Clin Invest(116): 2972-84, 2006. [Full Text/Abstract]
10. Furuya F, Hanover JA, Cheng SY Activation of phosphatidylinositol 3-kinase signaling by a mutant thyroid hormone beta receptor. Proc Natl Acad Sci U S A (103): 1780-5, 2006. [Full Text/Abstract]
11. Kim EJ, Perreira M, Thomas CJ, Hanover JA An O-GlcNAcase-Specific Inhibitor and Substrate Engineered by the Extension of the N-Acetyl Moiety. J Am Chem Soc (128): 4234-5, 2006. [Full Text/Abstract]
12. Forsythe ME, Love DC, Lazarus BD, Kim EJ, Prinz WA, Ashwell G, Krause MW, Hanover JA Caenorhabditis elegans ortholog of a diabetes susceptibility locus: oga-1 (O-GlcNAcase) knockout impacts O-GlcNAc cycling, metabolism, and dauer. Proc Natl Acad Sci U S A (103): 11952-7, 2006. [Full Text/Abstract]
13. Kim EJ, Kang DO, Love DC, Hanover JA Enzymatic characterization of O-GlcNAcase isoforms using a fluorogenic GlcNAc substrate. Carbohydr Res , 2006. [Full Text/Abstract]
14. Perreira M, Kim EJ, Thomas CJ, Hanover JA Inhibition of O-GlcNAcase by PUGNAc is dependent upon the oxime stereochemistry. Bioorg Med Chem (14): 837-46, 2006. [Full Text/Abstract]
15. Lazarus BD, Love DC, Hanover JA Recombinant O-GlcNAc transferase isoforms: identification of O-GlcNAcase, yes tyrosine kinase, and tau as isoform-specific substrates. Glycobiology (16): 415-21, 2006. [Full Text/Abstract]
16. Hanover JA, Forsythe ME, Hennessey PT, Brodigan TM, Love DC, Ashwell G, Krause M A Caenorhabditis elegans model of insulin resistance: altered macronutrient storage and dauer formation in an OGT-1 knockout. Proc Natl Acad Sci U S A (102): 11266-71, 2005. [Full Text/Abstract]
17. Disbrow GL, Hanover JA, Schlegel R Endoplasmic reticulum-localized human papillomavirus type 16 E5 protein alters endosomal pH but not trans-Golgi pH. J Virol (79): 5839-46, 2005. [Full Text/Abstract]
18. Bar-Sinai A, Bassa N, Fischette M, Gottesman MM, Love DC, Hanover JA, Hochman J Mouse mammary tumor virus Env-derived peptide associates with nucleolar targets in lymphoma, mammary carcinoma, and human breast cancer. Cancer Res (65): 7223-30, 2005. [Full Text/Abstract]
19. Lazarus BD, Roos MD, Hanover JA Mutational analysis of the catalytic domain of O-linked N-acetylglucosaminyl transferase. J Biol Chem (280): 35537-44, 2005. [Full Text/Abstract]
20. Love DC, Hanover JA The hexosamine signaling pathway: deciphering the "O-GlcNAc code". Sci STKE (2005): re13, 2005. [Full Text/Abstract]
21. Tang DC, Zhu J, Liu W, Chin K, Sun J, Chen L, Hanover JA, Rodgers GP The hydroxyurea-induced small GTP-binding protein SAR modulates gamma-globin gene expression in human erythroid cells. Blood (106): 3256-63, 2005. [Full Text/Abstract]
22. Wu CJ, Conze DB, Li X, Ying SX, Hanover JA, Ashwell JD TNF-alpha induced c-IAP1/TRAF2 complex translocation to a Ubc6-containing compartment and TRAF2 ubiquitination. EMBO J (24): 1886-98, 2005. [Full Text/Abstract]
23. Jinek M, Rehwinkel J, Lazarus BD, Izaurralde E, Hanover JA, Conti E The superhelical TPR-repeat domain of O-linked GlcNAc transferase exhibits structural similarities to importin alpha. Nat Struct Mol Biol (11): 1001-7, 2004. [Full Text/Abstract]
24. Vocadlo DJ, Hang HC, Kim EJ, Hanover JA, Bertozzi CR A chemical approach for identifying O-GlcNAc-modified proteins in cells. Proc Natl Acad Sci U S A (100): 9116-21, 2003. [Full Text/Abstract]
25. Zhang M, Sun M, Dwyer NK, Comly ME, Patel SC, Sundaram R, Hanover JA, Blanchette-Mackie EJ Differential trafficking of the Niemann-Pick C1 and 2 proteins highlights distinct roles in late endocytic lipid trafficking. Acta Paediatr Suppl (92): 63-73; discussion 45, 2003. [Full Text/Abstract]
26. Tsai WC, Bhattacharyya N, Han LY, Hanover JA, Rechler MM Insulin inhibition of transcription stimulated by the forkhead protein Foxo1 is not solely due to nuclear exclusion. Endocrinology (144): 5615-22, 2003. [Full Text/Abstract]
27. Hanover JA, Yu S, Lubas WB, Shin SH, Ragano-Caracciola M, Kochran J, Love DC Mitochondrial and nucleocytoplasmic isoforms of O-linked GlcNAc transferase encoded by a single mammalian gene. Arch Biochem Biophys (409): 287-97, 2003. [Full Text/Abstract]
28. Love DC, Kochan J, Cathey RL, Shin SH, Hanover JA Mitochondrial and nucleocytoplasmic targeting of O-linked GlcNAc transferase. J Cell Sci (116): 647-54, 2003. [Full Text/Abstract]
29. Chauhan SS, Liang XJ, Su AW, Pai-Panandiker A, Shen DW, Hanover JA, Gottesman MM Reduced endocytosis and altered lysosome function in cisplatin-resistant cell lines. Br J Cancer (88): 1327-34, 2003. [Full Text/Abstract]
30. McClain, DA, Lubas, WA, Cooksey, RC, Hazel, M, Parker, GJ, Love DC, Hanover, JA Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia. Proc Natl Acad Sci U S A(99): 10695-9, 2002.
31. Thakurta AG, Whalen WA, Yoon JH, Bharathi A, Kozak L, Whiteford C, Love DC, Hanover JA, Dhar R Crp79p, like Mex67p, is an auxiliary mRNA export factor in Schizosaccharomyces pombe. Mol Biol Cell (13): 2571-84, 2002. [Full Text/Abstract]
32. Zhang M, Liu P, Dwyer NK, Christenson LK, Fujimoto T, Martinez F, Comly M, Hanover JA, Blanchette-Mackie EJ, Strauss JF 3rd MLN64 mediates mobilization of lysosomal cholesterol to steroidogenic mitochondria. J Biol Chem (277): 33300-10, 2002. [Full Text/Abstract]
33. Lin HM, Kaneshige M, Zhao L, Zhang X, Hanover JA, Cheng SY An isoform of branched-chain aminotransferase is a novel co-repressor for thyroid hormone nuclear receptors. J Biol Chem (276): 48196-205, 2001. [Full Text/Abstract]
34. Holaska JM, Black BE, Love DC, Hanover JA, Leszyk J, Paschal BM Calreticulin Is a receptor for nuclear export. J Cell Biol (152): 127-40, 2001. [Full Text/Abstract]
35. Zhang M, Dwyer NK, Love DC, Cooney A, Comly M, Neufeld E, Pentchev PG, Blanchette-Mackie EJ, Hanover JA Cessation of rapid late endosomal tubulovesicular trafficking in Niemann-Pick type C1 disease. Proc Natl Acad Sci U S A (98): 4466-71, 2001. [Full Text/Abstract]
36. Hanover JA Glycan-dependent signaling: O-linked N-acetylglucosamine. FASEB J (15): 1865-76, 2001. [Full Text/Abstract]
37. Zhang M, Dwyer NK, Neufeld EB, Love DC, Cooney A, Comly M, Patel S, Watari H, Strauss JF 3rd, Pentchev PG, Hanover JA, Blanchette-Mackie EJ Sterol-modulated glycolipid sorting occurs in niemann-pick C1 late endosomes. J Biol Chem (276): 3417-25, 2001. [Full Text/Abstract]
38. Cui Y, Li M, Walton KD, Sun K, Hanover JA, Furth PA, Hennighausen L The Stat3/5 locus encodes novel endoplasmic reticulum and helicase-like proteins that are preferentially expressed in normal and neoplastic mammary tissue. Genomics (78): 129-34, 2001. [Full Text/Abstract]
39. Bustamante JO, Michelette ER, Geibel JP, Dean DA, Hanover JA, McDonnell TJ Calcium, ATP and nuclear pore channel gating. Pflugers Arch (439): 433-44, 2000. [Full Text/Abstract]
40. Bustamante JO, Michelette ER, Geibel JP, Hanover JA, McDonnell TJ, Dean DA Dendrimer-assisted patch-clamp sizing of nuclear pores. Pflugers Arch (439): 829-37, 2000. [Full Text/Abstract]
41. Lubas WA, Hanover JA Functional expression of O-linked GlcNAc transferase. Domain structure and substrate specificity. J Biol Chem (275): 10983-8, 2000. [Full Text/Abstract]
42. Dace A, Zhao L, Park KS, Furuno T, Takamura N, Nakanishi M, West BL, Hanover JA, Cheng S Hormone binding induces rapid proteasome-mediated degradation of thyroid hormone receptors. Proc Natl Acad Sci U S A (97): 8985-90, 2000. [Full Text/Abstract]
43. Yoon JH, Love DC, Guhathakurta A, Hanover JA, Dhar R Mex67p of Schizosaccharomyces pombe interacts with Rae1p in mediating mRNA export. Mol Cell Biol (20): 8767-82, 2000. [Full Text/Abstract]
44. Soukharev S, Berlin W, Hanover JA, Bethke B, Sauer B Organization of the mouse ASGR1 gene encoding the major subunit of the hepatic asialoglycoprotein receptor. Gene (241): 233-40, 2000. [Full Text/Abstract]
45. Sweitzer TD, Love DC, Hanover JA Regulation of nuclear import and export. Curr Top Cell Regul (36): 77-94, 2000. [Full Text/Abstract]
46. Roos MD, Hanover JA Structure of O-linked GlcNAc transferase: mediator of glycan-dependent signaling. Biochem Biophys Res Commun (271): 275-80, 2000. [Full Text/Abstract]
47. Kurys G, Tagaya Y, Bamford R, Hanover JA, Waldmann TA The long signal peptide isoform and its alternative processing direct the intracellular trafficking of interleukin-15. J Biol Chem (275): 30653-9, 2000. [Full Text/Abstract]