[PTHE Membership Roster] [PTHE Meeting Rosters]
The Pathogenic Eukaryotes [PTHE] Study Section reviews applications involving protozoal, helminthic, fungal pathogens in humans and animal models. Specific areas covered by PTHE:
- Mechanisms of pathogenesis including: pathogen-host cell receptor interactions, signaling pathways in both host cell and pathogen, molecular mechanisms of virulence, manipulation of host cell biological pathways, and factors associated with asymptomatic infection and/or commensalisms
- Primary host defenses including: genetic basis of host resistance and susceptibility to infection and disease, induction and regulation of innate and acquired immunity, evasion of host immune response
- Biochemical processes of the pathogen including: metabolism, enzymology, physiology, and replication
- Identification and preclinical validation of potential chemotherapeutic targets and diagnostic strategies
- Pathogen cell biology including: novel organelles, secretory processes, and mechanisms of motility
- Pathogen differentiation, morphogenesis, and developmental processes required for the infectious cycle including transmission and persistence
- Genetic processes including: gene structure, regulation of gene expression, molecular evolution, genetic diversity, and improved genetic methodology
- Functional genomics, comparative genomics, proteomics, and other broad-based technologies for studying genomes
- Improved models of infectious cycles and diseases
Study sections with most closely related areas of similar science listed in rank order are:
Drug Discovery and Mechanisms of Antimicrobial Resistance [DDR] Innate Immunity And Inflammation [III] Immunity and Host Defense [IHD] Vector Biology [VB] AIDS-associated Opportunistic Infections and Cancer [AOIC]
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