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Pancreatic Cancer Risk Indentified in Male Smokers with Insulin
Resistance
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Brief Description:
A new study led by researchers at the National Cancer Institute shows that male smokers
with elevated insulin levels — measured after an overnight fast — were
twice as likely to develop pancreatic cancer as men with the lowest levels.
Transcript:
Schmalfeldt:A new study led by researchers at the National Cancer
Institute shows that male smokers with elevated insulin levels — measured after
an overnight fast — were twice as likely to develop pancreatic cancer as men
with the lowest levels. Also, men with glucose levels in the range of clinical diabetes
were twice as likely to develop the deadly form of cancer as men with normal levels.
The study examined 29-thousand male smokers in Finland. Doctor Racheal Stolzenberg-Solomon
of the NCI Division of Cancer Epidemiology and Genetics was lead researcher in the
study. She said that while these results are interesting, they are but a step in the
journey of discovery towards understanding the causes of pancreatic cancer.
Stolzenberg-Solomon: It's too early for this study to have clinical
applications, because first it needs to be replicated in another group that includes
women and non-smokers. What it could mean, though, is that there are things you can
do — lifestyle changes — that can decrease glucose and insulin concentrations
like weight reduction, increasing physical activity, and changing your diet so it has
less saturated fat. And doing those lifestyle changes not only could impact someone's
pancreatic cancer risk, but other cancers and other chronic diseases, too. It's just
a healthier way to be.
Schmalfeldt: It's estimated that almost 32-thousand people in the
United States will have died from pancreatic cancer in 2005. Only four percent of those
with the disease survive five years past the diagnosis. The study appears in the December
14th issue of the Journal of the American Medical Association. From the National Institutes
of Health, I'm Bill Schmalfeldt in Bethesda, Maryland.
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| Date: 12/15/2005 |
Reporter:
Bill Schmalfeldt |
Sound Bite:
Dr. Racheal Stolzenberg-Solomon |
Topic:
Cancer |
| Institute(s): NCI |
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