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Channels, synapses, and neural circuits are fundamental structural and functional elements of the nervous system. Detailed and integrated knowledge of these elements is essential for understanding how the nervous system works under normal and abnormal conditions. In recent years, remarkable progress and exciting discoveries have been made in the basic research in these areas; only few of them, however, have been directly connected to mechanisms underlying the causes of numerous neurological disorders. The major goals of our program are 1) to continue to support the ongoing basic and clinical research; 2) to foster research on particular channels, synapses, and neural circuits that have immediate medical relevance; and 3) encourage translational research that links the discoveries from basic research into medication development and therapeutic interventions for treating neurological disorders, such as epilepsy.

Topics of research supported by the Channels, Synapses, and Neural Circuits cluster include neural circuit analysis, synaptic transmission, synaptic plasticity, structural analysis of neuronal membrane proteins, channelopathies, and epilepsy.  The cluster supports basic and translational research, as well as clinical trials, and facilitates multidisciplinary collaborations.

Quick Links

• NINDS Epilepsy Information Page
  
• Epilepsy Research Web
  
• The "Benchmarks" For Epilepsy Research

Channels, Synapses, and Neural Circuits Funding Initiatives

• All Channels, Synapses, and Neural Circuits funding initiatives

Channels, Synapses, and Neural Circuits Program Staff

Scientific Staff	Research Area
Brandy Fureman, Ph.D. Program Director	Epilepsy
Shai Silberberg, Ph.D. Program Director	Molecular structure and function of ion channels and transporters
Randall Stewart, Ph.D. Program Director	Basic mechanisms of epilepsy and epileptogenesis, channelopathies, SBIR, STTR
Edmund Talley, Ph.D. Program Director	Synaptic transmission and neuromodulation
Lynn Rundhaugen, M.P.H. Program Analyst
Christina Vert, M.S. Program Analyst

Address

Channels, Synapses and Neural Circuits
Neuroscience Center
Room NSC 2110
6001 Executive Blvd.
Bethesda, Maryland 20892-9523
Phone: 301-496-1917
Fax: 301-480-2424