National Institute of Allergy and Infectious Diseases (NIAID)

136 Protocols (105 Active Accrual of new subjects, 31 Follow-up of previously enrolled subjects)

 09-I-0129:

A Randomized Double-Blinded, Placebo-Controlled Study of Omalizumab for Idiopathic Anaphylaxis

 09-I-0126:

Pathogenesis of Physical Induced Urticarial Syndromes

 09-I-0108:

Strategic Timing of AntiRetroviral Treatment (START)

 09-I-0102:

Etiology, Pathogenesis, and Natural History of Idiopathic CD4+ Lymphocytopenia

 09-I-0090:

VRC 307: A D/B Randomized Ph. I Study of Safety/Immunogenicity of a Prime-Boost Schedule of an Investigational DNA Influenza Vaccine, Followed by the Seasonal Influenza Trivalent Inactivated Vaccine (TIV), Compared to TIV Alone in Healthy Adults

 09-I-0086:

Screening Protocol for Genetic Diseases of Mast Cell Homeostasis and Activation

 09-I-0069:

Interleukin-7 (CYT107) Treatment of Idiopathic CD4 Lymphocytopenia: Expansion of CD4 T Cells (ICICLE)

 09-I-0049:

Normal Blood, Bone Marrow and Buccal Mucosa Protocol

 09-I-0030:

Clinical and Immunologic Monitoring of Patients with Known or Suspected HIV Infection

 09-I-0013:

Biomarkers of Inflammation, Coagulation, and Endothelial Function in HIV-Infected Adults

 09-I-0012:

An Open-Label, Randomized Phase I Study in Healthy Adults of 4 Prime-Boost Schedules with Monovalent Influenza Subunit Virion (H5N1) Vaccine (Sanofi Pasteur, Inc), Administered Alone or Following Recombinant DNA Plasmid (H5) Vaccine (VRC, NIAID)

 08-I-0221:

Analysis of HIV-1 Replication During Antiretroviral Therapy

 08-I-0201:

Pioglitazone for Hepatic Steatosis in HIV/HCV Co-infection

 08-I-0184:

Studies in the Pathogenesis of Idiopathic Anaphylaxis

 08-I-0171:

A Phase I, Open Label, CT to Evaluate the Safety, Tolerability and Immunogenicity of a Multiclade Recombinant HIV-1 Adenoviral Vector Vaccine, VRC-HIVADV014-00-VP In Uninfected Adults Randomized to Needle or Biojector Methods of Intramuscular Injection

 08-I-0065:

VRC 206: A Phase I Study to Evaluate the Safety and Immunogenicity of an Ebola DNA Plasmid Vaccine, VRC-EBODNA023-00-VP, and a Marburg DNA Plasmid Vaccine, VRC-MARDNA025-00-VP, in Healthy Adults

 08-I-0053:

Pilot (Phase I-II) Study of Valproic Acid (Depakote) for the Treatment of the Autoimmune Lymphoproliferative Syndrome (ALPS)

 08-I-0034:

Validation of (1)H-Magnetic Resonance Spectroscopy for Quantification of Hepatic Triglyceride Content

 07-I-0229:

Influenza in the Immunocompromised Host

 07-I-0218:

A Double-Blind, Randomized, Placebo-Controlled Cross-Over Study Assessing the Role of Pathogen-Specific IgE and Histamine Release in the Hyper-IgE Syndrome and the Effect of Ranitidine on Laboratory and Clinical Manifestations

 07-I-0205:

An Observational Study of the Immunopathogenesis of and Response to Step-Up Inflammatory Bowel Disease Therapy for Hermansky-Pudlak Syndrome-Associated Colitis

 07-I-0183:

The Collection of Research Samples and/or Data for Repository from Related or Unrelated Hematopoietic Stem Cell Transplantation Recipients for the National Marrow Donor Program

 07-I-0171:

Treatment for Growth Failure in Patients with X-Linked Severe Combined Immunodeficiency (XSCID): A Phase 2 Study Assessing Safety and Clinical Response to Treatment with Insulin-like Growth Factor-1 (IGF-1)

 07-I-0167:

VRC 012: A Phase I Clinical Trial of the Safety and Immunogenicity of an HIV-1 Adenoviral Vector Serotype 35 Vaccine: Dose Escalation as a Single Agent and Prime-Boost Schedules with an HIV-1 Adenoviral Vector Serotype 5 Vaccine in Uninfected Adults

 07-I-0155:

A Ph I/IIa Rand Placebo Ctrl, S-Blind Multictr Dose-Esc Study of SC Intermittent Interleukin-7 CYT107 in Chronically HIV-Infected Pts with CD4 T Lymphocyte Counts 101-400 Cells-/mm(3) and Plasma HIV RNA Less Than 50 copies/mL After at Least 12 M of HAART

 07-I-0142:

Research Respiratory Tract Procedures in Healthy Adult Volunteers and Adult Patients to Obtain Specimens for In Vitro Analyses of Infection Pathogenesis and Susceptibility

 07-I-0075:

Allogeneic and Matched Unrelated Donor Stem Cell Transplantation for Congenital Immunodeficiencies: Busulfan-based Conditioning with Campath- 1H or h-ATG, Radiation, and Sirolimus

 07-I-0033:

Screening Protocol for Detection and Characterization of Infections and Infection Susceptibility

 07-I-0017:

Autologous Transplantation of Genetically Modified Cells for the Treatment of X-Linked Chronic Granulomatous Disease

 07-I-0001:

An Open Label Non-Randomized Trial to Assess Safety and Tolerability of Alb-Interferon Alfa 2b Every Two Weeks with Ribavirin among HIV/HCV Coinfected Individuals

 06-I-0217:

Genetic Disorders of Mucociliary Clearance

 06-I-0207:

Investigation of Southern Tick-Associated Rash Illness (STARI)

 06-I-0160:

Infliximab Treatment for Crohn's-like Inflammatory Bowel Disease in Chronic Granulomatous Disease: A Phase I/II Study Assessing Clinical and Immune Responses to Treatment and Genetic Influences

 06-I-0153:

A Pilot Study of Hepatic Fibrosis in HIV/AIDS Patients with Chronically Elevated Transaminases on Antiretroviral Therapy

 06-I-0086:

A Cohort Observational Study Evaluating Predictors, Incidence and Immunopathogenesis of Immune Reconstitution Syndrome (IRIS) in HIV-1 Infected Patients with CD4 Count Less Than or Equal to 100 Cells/micro L Who Are Initiating Antiretroviral Therapy

 06-I-0077:

Voriconazole Plasma Concentration and Toxicity

 06-I-0074:

Collection of Blood from Persons with Hemoglobin and Erythrocyte Polymorphisms for Laboratory Malaria Research

 06-I-0049:

Studies of Disorders in Antibody Production and Related Primary Immunodeficiency States

 06-I-0032:

Pilot Study of Omalizumab (Xolair) in Hyper IgE (Job's) Syndrome

 06-I-0030:

Correlation of the Precursor Frequency of CD4 + Effector Memory T Cells with Induration Measured in the Tuberculin Skin Test (TST)

 06-I-0015:

Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell Death

 06-I-0005:

Evaluation of Risk Factors for Development of Epstein-Barr Virus Lymphoproliferative Disease

 05-I-0219:

Microarray Analysis of Erythema Migrans Lesions

 05-I-0213:

Screening and Baseline Assessment of Patients with Abnormalities of Immune Function

 05-I-0156:

A Study of Adjuvant Cytokine Therapy in Pulmonary Mycobacterium Avium Complex and other Pulmonary Nontuberculous Mycobacterial Infections

 05-I-0084:

Clinical and Immunological Evaluation of Children with Allergic Disease

 04-I-0286:

A Longitudinal Study of Familial Hypereosinophilia (FE): Natural History and Markers of Disease Progression

 04-I-0231:

Procurement of Clinical Specimens for Immunologic or Genetic Studies in Inflammatory Bowel Diseases

 04-I-0126:

Exhaled Breath Condensate as a Measurement of Airway Inflammation in Children with Asthma

 04-I-0086:

Leukapheresis Procedures to Obtain Plasma and Lymphocytes for Research on HCV-Infected Patients

 04-I-0030:

Clinical Evaluation and Management of Persons with Severe Acute Respiratory Syndrome (SARS)

 03-I-0285:

VRC 300: Screening of Healthy Volunteers for Clinical Trials of Investigational Vaccines to Prevent Infectious Diseases

 03-I-0263:

Apheresis and Specimen Collection Procedures to Obtain Plasma, Peripheral Blood Mononuclear Cells (PBMCs) and Other Specimens for Research Studies

 03-I-0090:

Immune Responses to Vaccinia Virus Vaccination

 03-I-0079:

Screening HIV-Infected Subjects for Vaccine Research Studies

 03-I-0041:

Determining the Pathogenesis of Systemic Pediatric-Onset Mastocytosis

 02-I-0308:

Study of Fluorodeoxyglucose Positron Emission Tomography (FDG-PET) for the Evaluation of the Autoimmune Lymphoproliferative Syndrome (ALPS) and ALPS-Associated Lymphoma

 02-I-0286:

A Pilot Study of the Safety and Efficacy of Imatinib Mesylate in Reducing Eosinophilia in Patients with the Myeloproliferative Variant Hypereosinophilic Syndrome (HES) or Non-Myeloproliferative HES Refractory to Standard Therapy

 02-I-0277:

Regulation of the Proliferation and Survival of Normal and Neoplastic Human Mast Cells

 02-I-0232:

HIV Expression in Patients with Viral Loads Suppressed on HAART

 02-I-0202:

Leukapheresis Procedures to Obtain Plasma and Lymphocytes for Research Studies on Antiretroviral Naive HIV-Infected Patients

 02-I-0147:

Genetic Studies of Chronic Active Epstein-Barr Virus Infection

 02-I-0127:

Screening Subjects for HIV Vaccine Research Studies

 02-I-0110:

Natural History of Anthrax: A Study of Primary Infected, Recovered, and Exposed (SPoRE) Individuals and Evaluation of AVA Vaccinated Recipients

 02-I-0096:

Rituximab (Anti-CD20) for the Treatment of Hepatitis C Associated Cryoglobulinemic Vasculitis

 02-I-0086:

Leukapheresis Procedures to Study HIV-Specific Immunity

 02-I-0055:

Evaluation, Treatment and Follow up of Patients with Lyme Disease

 01-I-0238:

Diagnosis and Treatment of Leishmanial Infections

 01-I-0226:

Evaluation of Immune Response to Vaccines in Primary Immune Disorders

 01-I-0225:

An Omnibus Proleukin (IL-2) Trial in HIV-Infected Patients Including Interrupted Versus Continuous Antiretrovirals (OPTICA): A Substudy of Interrupted Versus Continuous Antiretrovirals Involving Randomization From the Umbrella Study (ICARUS)

 01-I-0202:

Natural History, Genetics, Phenotype and Treatment of Mycobacterial Infections

 01-I-0161:

Identification of Novel Viruses

 01-I-0153:

The Immune Basis for the Gastrointestinal Complications of Common Variable Immunodeficiency

 01-I-0004:

An Assessment of the Relationship Between Antiretroviral Drug Genotype/Phenotype (IC50) and Antiretroviral Activity in HIV-Infected, Drug-Experienced Patients with Suboptimal Suppression of Plasma Viral Load

 00-I-0159:

Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection (Job) Syndrome

 00-I-0099:

Langherhans' Cell Function and Inflammatory Responses in Skin of Normal Volunteers and Patients with Helminth Infections Using the Suction Blister Technique

 99-I-0084:

To Develop a New Technique to Predict the Occurrence of Pneumocystis Pneumonia, Track its Epidemiology, Diagnose Acute Disease, and Predict and Monitor the Response to Various Therapeutic Agents

 98-I-0070:

Magnetic Resonance Imaging to Study Avascular Necrosis in HIV-Infected Subjects

 98-I-0027:

The Characterization of CD34+ Derived Mast Cell Precursors Mobilized by Administration of Granulocyte Colony Stimulating Factor

 97-I-0191:

Studies of Lymphocyte Kinetics Using Stable Isotopes

 97-I-0096:

Evaluation, Treatment, and Monitoring of Patients With Known or Suspected Parasitic Infection

 96-I-0129:

Evaluation and Long Term Follow-up of Patients with Allergic and Inflammatory Disorders

 96-I-0085:

Genetic Studies of the X-Linked Lymphoproliferative Disease

 96-I-0052:

A Comprehensive Clinical, Microbiological and Immunological Assessment of Patients with Suspected Chronic Lyme Infection and Selected Control Populations

 95-I-0066:

Genetic Analysis of Immune Disorders

 95-I-0027:

Virologic and Immunologic Evaluation of Lymph Node, Tonsillar, and Intestinal Biopsies, and Bronchoalveolar Lavage Fluid

 94-I-0079:

Eosinophil Activation and Function in Parasitic Infections and Other Conditions with Increased Tissue or Peripheral Blood Eosinophilia in Humans

 94-I-0073:

Recruitment of Peripheral Blood Hematopoietic Progenitors by Granulocyte Colony Stimulating Factor (G-CSF)

 93-I-0119:

Detection and Characterization of Host Defense Defects

 93-I-0106:

Cryptococcosis in Previously Normal Adults

 93-I-0086:

Evaluation and Long Term Follow Up of Patients with Acute or Chronic Inflammatory Disorders

 93-I-0063:

Study of the Immunopathogenesis, Natural History, and Genetics of Autoimmune Lymphoproliferative Syndrome (ALPS) Associated with an Expansion of CD4-8-/TCR alpha/beta+ T Cells

 93-I-0057:

Apheresis Procedures to Obtain Plasma or Leukocytes for In Vitro Studies

 92-I-0125:

A Study of Viral Burden in Peripheral Blood Versus Lymphoid and Bone Marrow Tissue in HIV-Infected Individuals

 91-I-0140:

Studies of the Pathogenesis of HIV Infection in Human Peripheral Blood Cells and/or Reproductive Fluids in HIV-Infected and HIV-Uninfected Volunteers

 90-I-0120:

Comparison of Inflammatory Responses in Normal Volunteers and Patients with Abnormal Phagocyte Function Using the Suction Blister Technique

 89-I-0174:

Study of Patients with Known or Suspected Infection with Strongyloides Stercoralis

 89-I-0158:

Studies of Immune Regulation in Patients with Common Variable Immunodeficiency and Related Humoral Immunodeficiency Syndromes

 88-I-0083:

Host Response to Infection and Treatment in the Filarial Diseases of Humans

 87-I-0163:

Apheresis Procedures to Obtain Plasma or Leukocytes for In Vitro Studies

Next 36 Protocols

Search The Studies | Help | Questions |
Clinical Center Home | NIH Home

National Institutes of Health Clinical Center
Bethesda, Maryland 20892. Last update: 05/05/2009