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Cirrhotic macrophages elicit CB1-mediated hypotension


The illustration below is from Vol 7 pp. 827-32, 2001 of Nature Medicine
Cirrhotic macrophages elicit CB1-mediated hypotension
The hypotensive response of normal recipient rats to the injection of monocytes isolated from rats with biliary cirrhosis. Monocytes isolated from 5 ml of blood from control rats (o), or from cirrhotic rats were injected at 0 min into recipient rats pretreated with 3 mg/kg vehicle (o) or SR141716A, (o). Cells were injected in 200 L of saline at 0 min. Points and bars represent means s.e.; n = 6–10. *, significant difference from corresponding baseline (0 min) values.



Updated: August 2002

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