IN THIS ISSUE . .
.
Winter/Spring 2009
SPECIAL NOTICE:
Learn How NCRR Is Contributing to America's Economic Recovery
DIRECTOR'S
MESSAGE:
Guiding Successful Careers to the Intersection of Basic, Clinical and Community Sciences
COVER STORY:
An Eye to the Future: Training the Next Generation of Researchers
The CTSA consortium provides access to critical training opportunities for junior investigators.
CTSAs IN FOCUS:
Updates on the Clinical and Translational Science Awards
CRITICAL RESOURCES:
The Business End of Translational Research
University science and business faculties work together to advance science and medicine.
RESOURCE BRIEFS:
Peering More Deeply into Proteins
A New Way to Preserve Fish
NEWS FROM
NCRR:
People,
Awards, Grants and New
Developments
Web Exclusives:
What's New, Upcoming Events, Funding Opportunities
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SPECIAL NOTICE:
Learn How NCRR Is Contributing to America's Economic Recovery
NCRR will administer more than $1.6 billion in federal grants under the American Recovery and Reinvestment Act of 2009 in areas such as construction, repair and renovation of research facilities; shared instrumentation and other capital research equipment; and biomedical research.
Visit www.ncrr.nih.gov/recovery to see plans, funding opportunities and more.
DIRECTOR'S MESSAGE:
Guiding Successful Careers to the Intersection of Basic, Clinical and Community Sciences
Translation of research advances to practices that will improve human health cannot
occur without a cadre of well-trained translational and clinical researchers. The new issue of the NCRR Reporter highlights examples of training programs offered at three Clinical and Translational Science Award institutions and the individuals who have benefited from them, charting their own paths to successful careers. Read more.
COVER STORY:
An Eye to the Future: Training the Next Generation of Researchers
The CTSA consortium provides access to critical training opportunities
for junior investigators.
Future translational researchers are now benefiting from the training and education provided through innovative programs at medical institutions across the nation with support from NCRR’s Clinical and Translational Science Award (CTSA) program. Although these training programs have diverse strengths and goals, they share the common mission of providing junior investigators with the knowledge, skills and resources they need to conduct science that will improve human health. Read more.
CTSAs IN FOCUS:
Updates on the Clinical and Translational Science Awards
Informatics Pilot Projects
to Aid Scientists Nationwide
NIH has awarded three contracts totaling an estimated $4 million for pilot projects to improve informatics support for researchers conducting small- to medium-sized clinical studies. Read more.
Awards Fund Clinical Research Network Collaboration
Clinical Research Network Feasibility Awards went to six CTSA institutions in 2009, providing each with funding for one year. Read more.
West Coast Consortium Working to Accelerate Research
Many CTSA research institutions are now forming regional consortia. The evolving consortia are designed to find commonalities and complementary strengths to further accelerate clinical and translational research. Read more.
New Google Search Feature on CTSAweb.org
A new search feature on the CTSA consortium’s Web site, www.CTSAweb.org, provides access to content from CTSAweb.org and individual CTSA institution Web sites in one easy step. Read more.
CRITICAL RESOURCES:
The Business End of Translational Research
University science and business faculties work together to advance science and medicine.
With its focus on multidisciplinary collaboration, the Clinical and Translational Science Award (CTSA) program creates an environment in which business principles can inform scientific development, speeding up the translational process. A number of CTSA grantees have forged relationships with business schools that take advantage of a natural synergy of resources. Read more.
RESOURCE BRIEFS:
Peering More Deeply into Proteins
A new protocol developed at the National Center for Macromolecular Imaging (NCMI) by Director Wah Chiu and his colleagues provides greater insight into protein structures, which might lead to the design of better drug interventions, ultimately helping to improve human health. Read more.
A New Way to Preserve Fish
Some fish species, like zebrafish and medaka, have become important models for human disease research and developmental biology studies. But freezing methods that allow researchers to share these animals are often slow, laborious and inconsistent. Now, researchers at Louisiana State University's Agricultural Center have received funding from NCRR to standardize the freezing process and expand it to a wider scale. Read more.
NEWS FROM NCRR:
People, Awards, Grants and New
Developments
Web Exclusives
What's New:
Upcoming Events:
Clinical and Translational Science Award (CTSA) Consortium. CTSAweb.org offers the latest information on institution and consortium events.
Read more.
Detection, Impact and Control of Specific Pathogens in Animal Resource Facilities. The broad purpose of this April 23–24 workshop is to identify current problems and future challenges related to the control, detection, research interpretation and zoonotic potential of emerging and re-emerging pathogens in animal resource facilities.
Read more.
Improving Health WITH Communities: The Role of Community Engagement in Clinical and Translational Research. This May 14–15 conference will highlight best practices for collaborations among communities and health care providers to improve health. Participants also will develop recommendations for academic-community collaborations and partnerships with other community programs to establish research agendas. Read more.
Funding Opportunities:
- Recovery Act-Related Notice: Administrative Supplements for NCRR Awards invites investigators and U.S. institutions or organizations with active NIH research grants to request administrative supplements for the purpose accelerating the tempo of scientific research on active grants. Read more.
- Recovery Act-Related Notice: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications announces the opportunity for investigators and United States institutions and organizations with active NIH-supported research project grants, including SBIR and STTR, to submit revision applications (formerly termed competitive supplements) to support a significant expansion of the scope or research protocol of approved and funded projects. Read more.
- Recovery Act-Related Notice: NIH Announces the Availability of Recovery Act Funds for Administrative Supplements Providing Summer Research Experiences for Students and Science Educators announces the opportunity for investigators and United States institutions and organizations with active NIH research grants to request administrative supplements for the purpose of promoting job creation, economic development and accelerating the pace and achievement of scientific research. Read more.
- Recovery Act-Related Notice: NIH Announces the Availability of Recovery Act Funds for Administrative Supplements announces the opportunity for investigators and United States institutions and organizations with active NIH research grants to request administrative supplements for the purpose accelerating the tempo of scientific research on active grants. Read more.
- Recovery Act-Related Notice: Addition of Recovery Funds to the Shared Instrumentation Grant Program (S10) announces $300 million for shared instrumentation and other capital research equipment, as well as $1 billion for grants or contracts under section 481A of the Public Health Service Act to construct, repair or renovate existing non-federal research facilities. Read more.
- Recovery Act Limited Competition: High-End Instrumentation Grant Program (S10) encourages applications from groups of NIH-supported investigators to purchase a single major item of equipment to be used for biomedical research that costs at least $600,000. The maximum award is $8 million. Additionally, it is expected that the funds will be expended expeditiously, within 18 to 24 months from the date of award. Read more.
- Recovery Act Limited Competition: Extramural Research Facilities Improvement Program (C06) is intended to facilitate and enhance the conduct of Public Health Service-supported biomedical and behavioral research by supporting the costs of improving non-federal basic research, clinical research and animal facilities to meet the biomedical or behavioral research, research training or research support needs of an institution. Read more.
- Recovery Act Limited Competition: Core Facility Renovation, Repair and Improvement (G20) provides funding to upgrade core facilities that support the conduct of PHS supported biomedical and/or behavioral research. Support can be requested to alter and renovate the core facility as well as to improve the general equipment in the core facility or to purchase general equipment for specialized groups of researchers. Read more.
- Recovery Act Limited Competition: NIH Challenge Grants in Health and Science Research (RC1) support research on topic areas which address specific scientific and health research challenges in biomedical and behavioral research that would benefit from significant two-year jumpstart funds. NIH institutes and centers have selected specific challenge topics within each of the challenge areas. Read more.
- Solicitation of Assays for High Throughput Screening (HTS) in the Molecular Libraries Probe Production Centers Network (R03) encourage HTS assay applications from investigators who have the interest and capability to work with the Molecular Libraries Probe Production Centers Network for chemical probe development. Read more.
- Clinical Research Curriculum Award (K30) is intended to stimulate the inclusion of high-quality didactic training as part of the career development of clinical investigators from diverse scientific backgrounds and disciplines. These programs prepare undergraduate, predoctoral or postdoctoral candidates to conduct research in team settings that are highly interdisciplinary and collaborative. Read more.
- Manufacturing Processes of Medical, Dental and Biological Technologies (SBIR R43/R44) encourages eligible U.S. small businesses to submit SBIR phase I, phase II and fast-track grant applications that propose the conduct of biomedical research related to advanced processing, manufacturing processes, equipment and systems, and manufacturing workforce skills and protection. Read more.
- Manufacturing Processes of Medical, Dental and Biological Technologies (STTR R41/R42) encourages eligible United States small businesses to submit STTR phase I, phase II and fast-track grant applications that propose the conduct of biomedical research related to advanced processing, manufacturing processes, equipment and systems, and manufacturing workforce skills and protection. Read more.
- Notice of Availability of Administrative Supplements for Research on Outcome Measures for Pediatric Clinical Trials in Support of the Best Pharmaceuticals for Children Act announces an administrative supplement program to provide funds to Clinical and Translational Science Award consortium-supported research projects for research on outcome measures in clinical and translational child health in priority areas as determined by the Best Pharmaceuticals for Children Act program administered by NICHD. Read more.
- Energy Efficiency and Renewable Energy System Technology Research and Development (SBIR R43/R44) encourages eligible U.S small businesses whose biomedical research is related to energy efficiency or renewable energy systems to submit SBIR phase I, phase II and fast-track grant applications for R&D projects in those areas. Read more.
- Energy Efficiency and Renewable Energy System Technology Research and Development (STTR R41/R42) encourages eligible U.S small businesses whose biomedical research is related to energy efficiency or renewable energy systems to submit STTR phase I, phase II and fast-track grant applications for R&D projects in those areas. Read more.
- PHS 2009-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR R41/R42) invites eligible U.S. small businesses to submit Small Business Technology Transfer grant applications. Read more.
- PHS 2009-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR R43/R44) invites eligible U.S. small businesses to submit Small Business Innovation Research grant applications. Read more.
- Centers of Biomedical Research Excellence (COBRE P20) invites applications for Centers of Biomedical Research Excellence from investigators at biomedical research institutions that award doctoral degrees in the health sciences or sciences related to health or at independent biomedical research institutes within Institutional Development Award-eligible states. Read more.
- Institutional Clinical and Translational Science Award (U54) assists institutions to create an integrated academic home for clinical and translational science that has the resources to train and advance multidisciplinary and interdisciplinary investigators and research teams equipped with innovative research tools and information technologies to improve patient care. Read more.
- Probes for Microimaging the Nervous System (SBIR R43/R44) invites Small Business Innovation Research grant applications that propose research and development of probes useful in imaging the structure and function of the brain and other parts of the nervous system with award duration and amounts greater than those routinely allowed under the SBIR programs. Read more.
- Tools for Germplasm Cryopreservation (SBIR R43/R44) solicits applications for Small Business Innovation Research projects that propose innovative research in the areas of animal germplasm cryopreservation methods, reagents, equipment, biosecurity and the detection of disease, including the vertical transmission of disease. Read more.
- Tools for Germplasm Cryopreservation (STTR R41/R42) solicits applications for Small Business Technology Transfer projects that propose innovative research in the areas of animal germplasm cryopreservation methods, reagents, equipment, biosecurity and the detection of disease, including the vertical transmission of disease. Read more.
- Midcareer Investigator Award in Mouse Pathobiology Research (K26) seeks to support established, outstanding pathobiologists by providing protected time for mouse pathobiology research and mentoring of beginning investigators. The target candidates are scientists engaged in mouse pathobiology research who are within 15 years of their specialty training. Read more.
- Development and Translation of Medical Technologies that Reduce Health Disparities (SBIR R43/R44) solicits Small Business Innovation Research grant applications that propose to develop and translate medical technologies aimed at reducing disparities in healthcare access and health outcomes. Read more.
- NIH Pathway to Independence Award (K99/R00) is designed to facilitate a timely transition from a mentored postdoctoral research position to a stable independent research position with independent NIH or other independent research support at an earlier stage than is currently the norm. Read more.
- Mentored Research Scientist Development Award (K01) provides support for a sustained period of "protected time" for intensive research career development under the guidance of an experienced mentor, or sponsor, in the biomedical, behavioral or clinical sciences, leading to research independence. Read more.
- Shared Instrumentation Grant Program (S10) solicits applications from groups of NIH-supported investigators to purchase or upgrade commercially available instruments that cost at least $100,000. The maximum award is $500,000. Types of instruments supported include confocal and electron microscopes, biomedical imagers, mass spectrometers, DNA sequencers, biosensors, cell sorters, X-ray diffraction systems and NMR spectrometers among others. Read more.
- Instrument Development for Biomedical Applications (R21) solicits innovative applications for the development of new or improved instrumentation for biomedical research. Projects should propose tools that can be used by a wide range of biomedical or clinical researchers, and are not limited to a specific organ or disease. Read more.
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