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Volume 3(3);  March 2006
Editorial
Drowning or Thirsting: The Extremes of Availability of Medical Information
The PLoS Medicine Editors
PLoS Med. 2006 March; 3(3): e165. Published online 2006 March 28. doi: 10.1371/journal.pmed.0030165.
PMCID: PMC1420396
Synopses
Cardiovascular Disease Research: Time to Focus on Minority Ethnic Groups
PLoS Med. 2006 March; 3(3): e81. Published online 2006 January 3. doi: 10.1371/journal.pmed.0030081.
PMCID: PMC1324793
Detecting Clusters of MRSA
PLoS Med. 2006 March; 3(3): e84. Published online 2006 January 10. doi: 10.1371/journal.pmed.0030084.
PMCID: PMC1325476
Failures in the Management of Elderly Women with Breast Cancer
PLoS Med. 2006 March; 3(3): e92. Published online 2006 January 17. doi: 10.1371/journal.pmed.0030092.
PMCID: PMC1326260
Long-Term Outcome of Individuals with Borderline Thrombocytopenia
PLoS Med. 2006 March; 3(3): e93. Published online 2006 January 17. doi: 10.1371/journal.pmed.0030093.
PMCID: PMC1326255
How Group A Streptococci Hide in Macrophages
PLoS Med. 2006 March; 3(3): e95. Published online 2006 January 17. doi: 10.1371/journal.pmed.0030095.
PMCID: PMC1326259
Angiopoietin-2: A New Therapeutic Target for Preventing Lung Dysfunction in Sepsis?
PLoS Med. 2006 March; 3(3): e97. Published online 2006 January 24. doi: 10.1371/journal.pmed.0030097.
PMCID: PMC1334225
Race/Ethnicity, Lipoproteins, and Antiretroviral Therapy
PLoS Med. 2006 March; 3(3): e98. Published online 2006 January 24. doi: 10.1371/journal.pmed.0030098.
PMCID: PMC1334222
Hypoxia Responses: How Different Cells and Tumors React to Oxygen Shortage
PLoS Med. 2006 March; 3(3): e105. Published online 2006 January 24. doi: 10.1371/journal.pmed.0030105.
PMCID: PMC1334224
Toward an Individual Approach to Methadone Therapy of Heroin Addicts
PLoS Med. 2006 March; 3(3): e128. Published online 2006 February 7. doi: 10.1371/journal.pmed.0030128.
PMCID: PMC1360080
The PLoS Medicine Debate
What Are the Public Health Effects of Direct-to-Consumer Drug Advertising?
Elizabeth A Almasi, Randall S Stafford, Richard L Kravitz, and Peter R Mansfield
PLoS Med. 2006 March; 3(3): e145. Published online 2006 March 28. doi: 10.1371/journal.pmed.0030145.
PMCID: PMC1420390
Perspectives
Epidemiology As a Tool to Reveal Inequalities in Breast Cancer Care
Eduardo L Franco
PLoS Med. 2006 March; 3(3): e48. Published online 2006 January 17. doi: 10.1371/journal.pmed.0030048.
PMCID: PMC1326261
Antiretroviral Therapy and Dyslipidaemia: Unlocking the Code
Patrick W. G Mallon
PLoS Med. 2006 March; 3(3): e85. Published online 2006 January 24. doi: 10.1371/journal.pmed.0030085.
PMCID: PMC1351918
Angiopoietin-2: Modulator of Vascular Permeability in Acute Lung Injury?
Tomoki Hashimoto and Jean-Francois Pittet
PLoS Med. 2006 March; 3(3): e113. Published online 2006 February 7. doi: 10.1371/journal.pmed.0030113.
PMCID: PMC1360081
Health in Action
Where There Is No Internet: Delivering Health Information via the Blue Trunk Libraries
Pascal Mouhouelo, Auguste Okessi, and Marie-Paule Kabore
PLoS Med. 2006 March; 3(3): e77. Published online 2006 March 7. doi: 10.1371/journal.pmed.0030077.
PMCID: PMC1420373
Telemedicine in Rural India
Sanjit Bagchi
PLoS Med. 2006 March; 3(3): e82. Published online 2006 March 7. doi: 10.1371/journal.pmed.0030082.
PMCID: PMC1420376
Policy Forum
Evidence-Based Prescribing of Statins: A Developing World Perspective
H. T Ong
PLoS Med. 2006 March; 3(3): e50. Published online 2006 February 21. doi: 10.1371/journal.pmed.0030050.
PMCID: PMC1370919
Enrolling Women into HIV Preventive Vaccine Trials: An Ethical Imperative but a Logistical Challenge
Edward Mills, Stephanie Nixon, Sonal Singh, Sonam Dolma, Anjali Nayyar, and Sushma Kapoor
PLoS Med. 2006 March; 3(3): e94. Published online 2006 February 21. doi: 10.1371/journal.pmed.0030094.
PMCID: PMC1370922
Best Practice
How Can Doctors Help Their Patients to Return to Work?
Jos H Verbeek
PLoS Med. 2006 March; 3(3): e88. Published online 2006 March 28. doi: 10.1371/journal.pmed.0030088.
PMCID: PMC1420379
Learning Forum
Assessing Myocardial Perfusion after Myocardial Infarction
Houman Ashrafian, Girish Dwivedi, and Roxy Senior
PLoS Med. 2006 March; 3(3): e131. Published online 2006 March 28. doi: 10.1371/journal.pmed.0030131.
PMCID: PMC1420389
Research Articles
Long-Term Outcome of Otherwise Healthy Individuals with Incidentally Discovered Borderline Thrombocytopenia
Roberto Stasi, Sergio Amadori, John Osborn, Adrian C Newland, and Drew Provan
PLoS Med. 2006 March; 3(3): e24. Published online 2006 January 17. doi: 10.1371/journal.pmed.0030024.
PMCID: PMC1326262
Differences in Management of Older Women Influence Breast Cancer Survival: Results from a Population-Based Database in Sweden
Sonja Eaker, Paul W Dickman, Leif Bergkvist, Lars Holmberg, and The Uppsala/Örebro Breast Cancer Group
PLoS Med. 2006 March; 3(3): e25. Published online 2006 January 17. doi: 10.1371/journal.pmed.0030025.
PMCID: PMC1326256
Automated DNA Sequence-Based Early Warning System for the Detection of Methicillin-Resistant Staphylococcus aureus Outbreaks
Alexander Mellmann, Alexander W Friedrich, Nicole Rosenkötter, Jörg Rothgänger, Helge Karch, Ralf Reintjes, and Dag Harmsen
PLoS Med. 2006 March; 3(3): e33. Published online 2006 January 10. doi: 10.1371/journal.pmed.0030033.
PMCID: PMC1325475
Exclusion and Inclusion of Nonwhite Ethnic Minority Groups in 72 North American and European Cardiovascular Cohort Studies
Meghna Ranganathan and Raj Bhopal
PLoS Med. 2006 March; 3(3): e44. Published online 2006 January 3. doi: 10.1371/journal.pmed.0030044.
PMCID: PMC1324792
Excess Circulating Angiopoietin-2 May Contribute to Pulmonary Vascular Leak in Sepsis in Humans
Samir M Parikh, Tadanori Mammoto, Aylit Schultz, Hai-Tao Yuan, David Christiani, S. Ananth Karumanchi, and Vikas P Sukhatme
PLoS Med. 2006 March; 3(3): e46. Published online 2006 January 24. doi: 10.1371/journal.pmed.0030046.
PMCID: PMC1334221
Gene Expression Programs in Response to Hypoxia: Cell Type Specificity and Prognostic Significance in Human Cancers
Jen-Tsan Chi, Zhen Wang, Dimitry S. A Nuyten, Edwin H Rodriguez, Marci E Schaner, Ali Salim, Yun Wang, Gunnar B Kristensen, Åslaug Helland, Anne-Lise Børresen-Dale, Amato Giaccia, Michael T Longaker, Trevor Hastie, George P Yang, Marc J van de Vijver, and Patrick O Brown
PLoS Med. 2006 March; 3(3): e47. Published online 2006 January 24. doi: 10.1371/journal.pmed.0030047.
PMCID: PMC1334226
Associations among Race/Ethnicity, ApoC-III Genotypes, and Lipids in HIV-1-Infected Individuals on Antiretroviral Therapy
Andrea S Foulkes, David A Wohl, Ian Frank, Elaine Puleo, Stephanie Restine, Megan L Wolfe, Michael P Dube, Pablo Tebas, and Muredach P Reilly
PLoS Med. 2006 March; 3(3): e52. Published online 2006 January 24. doi: 10.1371/journal.pmed.0030052.
PMCID: PMC1334223
Viable Group A Streptococci in Macrophages during Acute Soft Tissue Infection
Pontus Thulin, Linda Johansson, Donald E Low, Bing S Gan, Malak Kotb, Allison McGeer, and Anna Norrby-Teglund
PLoS Med. 2006 March; 3(3): e53. Published online 2006 January 17. doi: 10.1371/journal.pmed.0030053.
PMCID: PMC1326258
Determining Effective Methadone Doses for Individual Opioid-Dependent Patients
Jodie A Trafton, Jared Minkel, and Keith Humphreys
PLoS Med. 2006 March; 3(3): e80. Published online 2006 February 7. doi: 10.1371/journal.pmed.0030080.
PMCID: PMC1360079
Correspondence and Other Communications
Mitochondria: More than Mitochondrial DNA in Cancer
Bora Baysal
PLoS Med. 2006 March; 3(3): e156. Published online 2006 March 28. doi: 10.1371/journal.pmed.0030156.
PMCID: PMC1420391
Clinical Trials Registration
Frank W Rockhold and Ronald L Krall
PLoS Med. 2006 March; 3(3): e157. Published online 2006 March 28. doi: 10.1371/journal.pmed.0030157.
PMCID: PMC1420392
Prioritizing Investment in Medical Education
Fawad Aslam
PLoS Med. 2006 March; 3(3): e159. Published online 2006 March 28. doi: 10.1371/journal.pmed.0030159.
PMCID: PMC1420393
Rational Choices for Allocating Antiretrovirals in Africa: Treatment Equity, Epidemiological Efficiency, and Feasibility
David P Wilson and Sally M Blower
PLoS Med. 2006 March; 3(3): e160. Published online 2006 March 28. doi: 10.1371/journal.pmed.0030160.
PMCID: PMC1420394
How to Take HIV Antiretroviral Medications on Time without a Watch in Rural Uganda
Marissa Maier, Mwebesa Bwana, Nneka Emenyonu, Larry Pepper, and David R Bangsberg
PLoS Med. 2006 March; 3(3): e161. Published online 2006 March 28. doi: 10.1371/journal.pmed.0030161.
PMCID: PMC1420395
Authors' Reply
Antonio Salas, Yong-Gang Yao, and Hans-Jürgen Bandelt
PLoS Med. 2006 March; 3(3): e166. Published online 2006 March 28. doi: 10.1371/journal.pmed.0030166.
PMCID: PMC1420397
Author's Reply
Karmela Krleža-Jerić
PLoS Med. 2006 March; 3(3): e167. Published online 2006 March 28. doi: 10.1371/journal.pmed.0030167.
PMCID: PMC1420398
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