| | Correspondence On the Process of Becoming a Great Scientist Morgan C Giddings PLoS Comput Biol. 2008 February; 4(2): e33. Published online 2008 February 15. doi: 10.1371/journal.pcbi.0040033.PMCID: PMC2242824 Education Comprehensive Analysis of Affymetrix Exon Arrays Using BioConductor Michał J Okoniewski and Crispin J Miller PLoS Comput Biol. 2008 February; 4(2): e6. Published online 2008 February 29. doi: 10.1371/journal.pcbi.0040006.PMCID: PMC2323405 Message From ISCB Getting Started in Biological Pathway Construction and Analysis Ganesh A Viswanathan, Jeremy Seto, Sonali Patil, German Nudelman, and Stuart C Sealfon PLoS Comput Biol. 2008 February; 4(2): e16. Published online 2008 February 29. doi: 10.1371/journal.pcbi.0040016.PMCID: PMC2323403 Review Computational Methods for Protein Identification from Mass Spectrometry Data Leo McHugh and Jonathan W Arthur PLoS Comput Biol. 2008 February; 4(2): e12. Published online 2008 February 29. doi: 10.1371/journal.pcbi.0040012.PMCID: PMC2323404 Research Articles Serotonin, Inhibition, and Negative Mood Peter Dayan and Quentin J. M Huys PLoS Comput Biol. 2008 February; 4(2): e4. Prepublished online 2007 November 27. Published online 2008 February 1. doi: 10.1371/journal.pcbi.0040004.PMCID: PMC2222921 Filling-In and Suppression of Visual Perception from Context: A Bayesian Account of Perceptual Biases by Contextual Influences Li Zhaoping and Li Jingling PLoS Comput Biol. 2008 February; 4(2): e14. Prepublished online 2007 December 13. Published online 2008 February 15. doi: 10.1371/journal.pcbi.0040014.PMCID: PMC2242827 Predicting the Receptive Range of Olfactory Receptors Rafi Haddad, Liran Carmel, Noam Sobel, and David Harel PLoS Comput Biol. 2008 February; 4(2): e18. Published online 2008 February 1. doi: 10.1371/journal.pcbi.0040018.PMCID: PMC2222922 Microarray Based Diagnosis Profits from Better Documentation of Gene Expression Signatures Dennis Kostka and Rainer Spang PLoS Comput Biol. 2008 February; 4(2): e22. Prepublished online 2008 January 2. Published online 2008 February 15. doi: 10.1371/journal.pcbi.0040022.PMCID: PMC2242819 Evolution of Complex Modular Biological Networks Arend Hintze and Christoph Adami PLoS Comput Biol. 2008 February; 4(2): e23. Prepublished online 2008 January 2. Published online 2008 February 8. doi: 10.1371/journal.pcbi.0040023.PMCID: PMC2233666 How Force Might Activate Talin's Vinculin Binding Sites: SMD Reveals a Structural Mechanism Vesa P Hytönen and Viola Vogel PLoS Comput Biol. 2008 February; 4(2): e24. Prepublished online 2008 January 1. Published online 2008 February 15. doi: 10.1371/journal.pcbi.0040024.PMCID: PMC2242828 Modeling Cancer Progression via Pathway Dependencies Elena J Edelman, Justin Guinney, Jen-Tsan Chi, Phillip G Febbo, and Sayan Mukherjee PLoS Comput Biol. 2008 February; 4(2): e28. Published online 2008 February 15. doi: 10.1371/journal.pcbi.0040028.PMCID: PMC2242820 Selective Adaptation in Networks of Heterogeneous Populations: Model, Simulation, and Experiment Avner Wallach, Danny Eytan, Shimon Marom, and Ron Meir PLoS Comput Biol. 2008 February; 4(2): e29. Published online 2008 February 15. doi: 10.1371/journal.pcbi.0040029.PMCID: PMC2242821 Stimulus Design for Model Selection and Validation in Cell Signaling Joshua F Apgar, Jared E Toettcher, Drew Endy, Forest M White, and Bruce Tidor PLoS Comput Biol. 2008 February; 4(2): e30. Published online 2008 February 15. doi: 10.1371/journal.pcbi.0040030.PMCID: PMC2323406 The Peri-Saccadic Perception of Objects and Space Fred H Hamker, Marc Zirnsak, Dirk Calow, and Markus Lappe PLoS Comput Biol. 2008 February; 4(2): e31. Published online 2008 February 15. doi: 10.1371/journal.pcbi.0040031.PMCID: PMC2242822 Synaptic Plasticity Can Produce and Enhance Direction Selectivity Sean Carver, Eatai Roth, Noah J Cowan, and Eric S Fortune PLoS Comput Biol. 2008 February; 4(2): e32. Prepublished online 2008 January 9. Published online 2008 February 15. doi: 10.1371/journal.pcbi.0040032.PMCID: PMC2242823 Computational and Experimental Analysis of Redundancy in the Central Metabolism of Geobacter sulfurreducens Daniel Segura, Radhakrishnan Mahadevan, Katy Juárez, and Derek R Lovley PLoS Comput Biol. 2008 February; 4(2): e36. Prepublished online 2008 January 11. Published online 2008 February 8. doi: 10.1371/journal.pcbi.0040036.PMCID: PMC2233667 Modeling an Evolutionary Conserved Circadian Cis-Element Eric R Paquet, Guillaume Rey, and Felix Naef PLoS Comput Biol. 2008 February; 4(2): e38. Prepublished online 2008 January 11. Published online 2008 February 15. doi: 10.1371/journal.pcbi.0040038.PMCID: PMC2242825 Control of Cation Permeation through the Nicotinic Receptor Channel Hai-Long Wang, Xiaolin Cheng, Palmer Taylor, J. Andrew McCammon, and Steven M Sine PLoS Comput Biol. 2008 February; 4(2): e41. Prepublished online 2008 January 14. Published online 2008 February 15. doi: 10.1371/journal.pcbi.0040041.PMCID: PMC2242826 Accurate Structural Correlations from Maximum Likelihood Superpositions Douglas L Theobald and Deborah S Wuttke PLoS Comput Biol. 2008 February; 4(2): e43. Prepublished online 2008 January 14. Published online 2008 February 15. doi: 10.1371/journal.pcbi.0040043.PMCID: PMC2242818 Genome Landscapes and Bacteriophage Codon Usage Julius B. Lucks, David R. Nelson, Grzegorz R. Kudla, and Joshua B. Plotkin PLoS Comput Biol. 2008 February; 4(2): e1000001. Published online 2008 February 29. doi: 10.1371/journal.pcbi.1000001.PMCID: PMC2266997 How Protein Stability and New Functions Trade Off Nobuhiko Tokuriki, Francois Stricher, Luis Serrano, and Dan S. Tawfik PLoS Comput Biol. 2008 February; 4(2): e1000002. Published online 2008 February 29. doi: 10.1371/journal.pcbi.1000002.PMCID: PMC2265470 Systematic Analysis of Pleiotropy in C. elegans Early Embryogenesis Lihua Zou, Sira Sriswasdi, Brian Ross, Patrycja V. Missiuro, Jun Liu, and Hui Ge PLoS Comput Biol. 2008 February; 4(2): e1000003. Published online 2008 February 29. doi: 10.1371/journal.pcbi.1000003.PMCID: PMC2265476 Stochastic Differential Equation Model for Cerebellar Granule Cell Excitability Antti Saarinen, Marja-Leena Linne, and Olli Yli-Harja PLoS Comput Biol. 2008 February; 4(2): e1000004. Published online 2008 February 29. doi: 10.1371/journal.pcbi.1000004.PMCID: PMC2265481 The Signaling Petri Net-Based Simulator: A Non-Parametric Strategy for Characterizing the Dynamics of Cell-Specific Signaling Networks Derek Ruths, Melissa Muller, Jen-Te Tseng, Luay Nakhleh, and Prahlad T. Ram PLoS Comput Biol. 2008 February; 4(2): e1000005. Published online 2008 February 29. doi: 10.1371/journal.pcbi.1000005.PMCID: PMC2265486 Multi-Scale Simulations Provide Supporting Evidence for the Hypothesis of Intramolecular Protein Translocation in GroEL/GroES Complexes Ivan Coluzza, Alfonso De Simone, Franca Fraternali, and Daan Frenkel PLoS Comput Biol. 2008 February; 4(2): e1000006. Published online 2008 February 29. doi: 10.1371/journal.pcbi.1000006.PMCID: PMC2265519 Diminished Self-Chaperoning Activity of the ΔF508 Mutant of CFTR Results in Protein Misfolding Adrian W. R. Serohijos, Tamás Hegedűs, John R. Riordan, and Nikolay V. Dokholyan PLoS Comput Biol. 2008 February; 4(2): e1000008. Published online 2008 February 29. doi: 10.1371/journal.pcbi.1000008.PMCID: PMC2265529 Computer-Based Screening of Functional Conformers of Proteins Héctor Marlosti Montiel Molina, César Millán-Pacheco, Nina Pastor, and Gabriel del Rio PLoS Comput Biol. 2008 February; 4(2): e1000009. Published online 2008 February 29. doi: 10.1371/journal.pcbi.1000009.PMCID: PMC2265533 A Novel Bayesian DNA Motif Comparison Method for Clustering and Retrieval Naomi Habib, Tommy Kaplan, Hanah Margalit, and Nir Friedman PLoS Comput Biol. 2008 February; 4(2): e1000010. Published online 2008 February 29. doi: 10.1371/journal.pcbi.1000010.PMCID: PMC2265534 Sensing and Integration of Erk and PI3K Signals by Myc Tae Lee, Guang Yao, Joseph Nevins, and Lingchong You PLoS Comput Biol. 2008 February; 4(2): e1000013. Published online 2008 February 29. doi: 10.1371/journal.pcbi.1000013.PMCID: PMC2265471 Mutations of Different Molecular Origins Exhibit Contrasting Patterns of Regional Substitution Rate Variation Navin Elango, Seong-Ho Kim, NISC Comparative Sequencing Program, Eric Vigoda, and Soojin V. Yi PLoS Comput Biol. 2008 February; 4(2): e1000015. Published online 2008 February 29. doi: 10.1371/journal.pcbi.1000015.PMCID: PMC2265638 Statistical Resolution of Ambiguous HLA Typing Data Jennifer Listgarten, Zabrina Brumme, Carl Kadie, Gao Xiaojiang, Bruce Walker, Mary Carrington, Philip Goulder, and David Heckerman PLoS Comput Biol. 2008 February; 4(2): e1000016. Published online 2008 February 29. doi: 10.1371/journal.pcbi.1000016.PMCID: PMC2289775 Identification of Synaptic Targets of Drosophila Pumilio Gengxin Chen, Wanhe Li, Qing-Shuo Zhang, Michael Regulski, Nishi Sinha, Jody Barditch, Tim Tully, Adrian R. Krainer, Michael Q. Zhang, and Josh Dubnau PLoS Comput Biol. 2008 February; 4(2): e1000026. Published online 2008 February 29. doi: 10.1371/journal.pcbi.1000026.PMCID: PMC2265480 Mouse Cognition-Related Behavior in the Open-Field: Emergence of Places of Attraction Anna Dvorkin, Yoav Benjamini, and Ilan Golani PLoS Comput Biol. 2008 February; 4(2): e1000027. Published online 2008 February 29. doi: 10.1371/journal.pcbi.1000027.PMCID: PMC2265485 |