[ F04B Roster ]

The F04B panel reviews fellowship applications covering structure and biophysical behavior and dynamics of biological macromolecules. This includes applications concerned with the structure-function relationships of proteins, nucleic acids, glycoproteins, lipid bilayers and membrane proteins; X-ray crystallography, multi-dimensional NMR, electron microscopy, circular dichroism, fluorescence, and computational methods; single molecule dynamics and interactions by fluorescence and microscopic techniques; and molecular interactions for defining and maintaining cellular shape and function.  Specific areas covered by F04B include:

• Proteomics, global approaches to protein function, and posttranslational modification
• Computational data mining for analysis of proteins and related microarrays
• Physical chemistry of biological macromolecules, including conformation and structure of proteins and nucleic acids
• Spectroscopic methods, including multi-dimensional nuclear magnetic resonance, X-ray crystallography, Raman and FTIR
• Protein and nucleic acid folding and conformation by experimental and computational methods 
• Thermodynamics of macromolecular interactions, including isothermal calorimetry
• Kinetic analyses, including pH or temperature jump methods
• Structure and physical chemistry of lipid bilayer membranes and related model systems
• Physical chemical instrumentation, including development of new approaches and application of computers to such instrumentation
• Indirect methods for structure and dynamics determinations, including fluorescence dye labeling and tethering
• Carbohydrate biochemistry and glycoproteins, including synthesis and processing
• Signal transduction at molecular or subcellular levels, including protein structure, function, and enzymology
• Extracellular matrix at molecular or subcellular levels
• Motility and cytoskeleton at molecular or subcellular levels

Fellowship panels with most closely related areas of similar science listed in rank order are:

Biochemical and Molecular Neuroscience Fellowship Panel [F03A] 
Biophysical and Physiological Neuroscience Fellowship Panel [F03B] 
Chemical and Bioanalytical Sciences Fellowship Panel [F04A] 
Cell Biology and Development Fellowship Panel [F05]