January 2006 Director's Status Report

• Budget and Appropriations
• Legislative Update
• Staff Changes
• Institute-Sponsored Meetings, Workshops, and Conferences
• General Information/Staff Awards
• Relevant Notices and Initiatives Published in the NIH Guide
  

BUDGET and APPROPRIATIONS

Status of FY 2005, 2006, and 2007 Budgets for NIA

FY 2005
In FY 2005, the NIA obligated $1,045.3 billion in appropriated money. Funds in the amount of $6.7 million or 0.63 percent were transferred from the NIA to support trans-NIH roadmap activities. NIA awarded 1,462 research project grants (RPGs), including 376 competing awards. The FY 2005 success rate for the Institute was 18.8 percent which compares to 20.8 percent in FY 2004 and 28.6 percent in FY 2003. The decline in last year’s success rate, expressed as the number of competing RPGs applications funded divided by the number of applications received, is a result of not only the decrease in the number of competing RPGs funded, but also an unanticipated growth in the numbers of investigator-initiated applications received, partially due to an increased number of amended applications.

Support levels for other key extramural funding mechanisms included 77 research centers for $83.7 million; 612 full-time training positions for $22.4 million; and a total of $62.3 million for research and development contracts.

FY 2006
On December 30th after three continuing resolutions, the FY 2006 appropriations bill for the NIH (P.L. 107-360) was signed into law. For NIH as a whole, after the 1% across-the-board reduction, the appropriations provide $28.4 billion. For the NIA, the FY 2006 appropriation is $1.037 billion, excluding $9.4 million targeted for roadmap activities. This represents a decrease of $8.1 million or .8% from FY 2005.

The NIH policy for research project grant (RPG) funding is to reduce all non-competing awards by 2.35 percent from committed levels and to provide no increase over FY 2005 in the average cost of competing awards. Except for RPGs, research careers, and research management and support (RMS), all mechanisms are reduced by approximately 1.1 percent. In-house activities supported by RMS are provided a 0.5 percent increase over the comparable FY 2005 level to partially defray the cost of mandatory increases such as the pay raise.

In FY 2006, the NIA estimates supporting 1,486 RPGs, including 429 new and competing awards. Support levels for other mechanisms include 77 research centers for $82.8 million; 242 other research grants, including 210 career awards, for $34.7 million; 589 full-time training positions for $22.1 million, and $65.1 million for research and development contracts

FY 2007
The NIH recently received an OMB “pass-back” for FY 2007. This will become the FY 2007 President’s budget request and will reflect the Administration’s requested amounts for the individual NIH Institutes and Centers. This budget will be submitted to the Congress in early February 2006 and subsequently it will become available to the public.

The following NIA budget mechanism table displays FY 2005 actual comparable obligations and the FY 2006 appropriation.

(Contact: Ms. Donna Casady, BO, 301-496-9147)

Total

* The FY 2005 column includes a comparable adjustment for the funding of the scientific review and evaluation grants

LEGISLATIVE UPDATE

I. Significant Legislative/Executive Action

1. FY 2006 Senate and House Appropriations Bills for NIH/NIA –

With the failure of H.R. 3010, to pass, the Labor, Health and Human Services, Education and Related Agencies Appropriations measure has been returned to conference for resolution. The NIH/NIA continue to operate on a continuing resolution (CR) that currently extends through December 17, 2005. The CR applies the terms of the FY 2005 appropriations for the period covered by the CR.

2. Newly Introduced Legislation

1. On October 27, Senators Joseph Lieberman (D-CT) and Orrin Hatch (R-UT) introduced S. 1292, the FairCare Act. A recent NIA-funded study finding published in the New England Journal of Medicine was cited in the bill’s introductory remarks. The cited study reported that fewer than 55 percent of all patients receive the appropriate medical care. Some of the FairCare provisions are:

a. Create a uniform method for collecting demographic information from patients in federally funded health programs to provide a foundation for further research on healthcare quality and disparities;

b. Establish a federal grant program within the Department of Health and Human Services (HHS) for data collection, quality improvement, and disparity reduction to ensure that hospitals and community health centers have the resources necessary to engage in the structural adjustments required to expand data collection;

c. Expand the ability of HHS’s REACH 2010 Community Grant Program, which helps healthcare providers and communities work together to eliminate disparities, to help more communities nationwide.

2. On November 16, Senators Orrin Hatch (R-UT) and Blanche Lincoln (D-AR), reintroduced S. 2010, the Elder Justice Act. The bill includes provisions of interest to NIH. S. 2010 would establish an Interagency Elder Justice Steering Committee within HHS, which would include NIA in its membership. S. 2010 would authorize the Secretary to award grants for the prevention, detection, assessment, and treatment of and intervention in elder abuse and require NIA to establish Centers of Excellence to specialize in research, clinical practice, and training on elder abuse. The bill was referred to the Senate Committee on Finance.

II. Congressional Briefings and Hearings

A. On October 21, at the request of David Moore, Association of American Medical Colleges (AAMC), Dr. Hodes spoke at a briefing for Hill Staff entitled “Combating Alzheimer’s Disease and Other Diseases Affecting Older People.” This is one in a series of briefings called “Fulfilling the Promise.” Dr. Steve Dekosky, an NIH/NIA grantee, presented his research on Alzheimer’s disease.

B. At the request of the Jacob Institute of Women’s Health, Dr. Sherry Sherman, Program Director, Clinical Aging and Reproductive Hormone Research, participated in a December 7 congressional briefing on hormone therapy and the communication of medical information. Dr. Sherman spoke about research findings on racial and ethnic differences in the menopause transition and communication issues regarding diverse populations of women.

III. Professional Organization and Outreach Activities

A. October 14, Society for Investigative Dermatology met with Dr. Hodes and NIA staff. Dr. Jill Carrington, Biology of Aging Program will serve as NIA science liaison for the group.

B. On October 26, Dr. Judith Salerno and NIA program staff met with the American Association of Orthopaedic Surgeons (AAOS).

C. Dr. Hodes and Program staff met with the AD Hoc Group for Medical Research Funding on November 9.

D. On December 7, Dr. Hodes and program staff met with Mr. Harry Johns, new CEO of the Alzheimer’s Association and other AA organizational leadership staff.

(Contact: Dr. Tamara Jones, NIA/OD, Ph: 401-451-8835)

STAFF CHANGES

Dr. Ying Tian joined the Geriatrics and Clinical Gerontology Program (GCG) as a Health Scientist Administrator for the Geriatrics Branch in July of 2005. Dr. Tian holds an M.D. and a Ph.D. in Pathophysiology. Her postdoctoral training at the National Institute of Child Health and Human Development (NICHD) was in Endocrinology with an emphasis on expression of angiotensin II receptor and regulation of G-protein receptor signaling pathway. Since 2001 she has been an Assistant Professor of Medicine at the Division of Endocrinology, Department of Medicine, Georgetown University, Washington, D.C. She was the Principal Investigator on three research grants funded by NIH and the National Kidney Foundation. Her research focused on etiology of age-related defects in renal concentration function and molecular mechanisms underlying functional renal senescence.

Ms. Kathleen (Kathie) Reed joined NIA on December 12, 2005, as the new Planning and Evaluation Officer. For the past six years, Ms. Reed served as Chief of the National Cancer Institute’s (NCI) Science Planning Branch in the Office of Science Planning and Assessment where she provided leadership for a broad range of NCI planning and reporting functions and actively participated in many trans-NIH activities. NIA thanks Dr. Tamara Jones for her services over the past five months as Acting Director of the Office of Planning and Evaluation (OPAE).

Dr. Edgar (Pete) Raymond Miller, III, joined the Clinical Research Branch of the Intramural Research Program (IRP) as a Staff Clinician. Dr. Miller was formerly an Associate Professor of Medicine and Associate Professor of Epidemiology at the Johns Hopkins University School of Medicine and the Bloomberg School of Public Health. He is a general internist with research interests in nutrition, renal disease and hypertension.

Ms. Linda Joy joined the Office of Communications and Public Liaison (OCPL) on January 3 as the Public Affairs section chief. Ms. Joy has had 21 years of professional communications experience including several years as a senior science writer and public affairs specialist at NIH and at the National Institute for Standards and Technology. She also has an extensive background in newspaper reporting.

Ms. Donna Casady has accepted the position of NIA Budget Officer. Ms. Casady graduated from the University of Maryland. She was recruited by the DHHS under the Outstanding Scholars Program and began her federal career in the area of grants management. She worked for several years in the NIH Office of the Director as a senior budget analyst in the Budget Policy and Resource Analysis Branch and from there moved on to the National Institute of Child Health and Human Development where she served as the Deputy Budget Officer.

Dr. Judith A. Finkelstein has accepted a position as Scientific Review Administrator (SRA) in the Integrative Functional Cognitive Neuroscience (IFCN) Integrated Review Groups (IRG), Division of Physiology and Pathology, at the Center for Scientific Review (CSR). She will start her new position on January 22, 2006. Dr. Finkelstein served as Program Director for Sensory/Motor Disorders of Aging in the Neuroscience and Neuropsychology of Aging Program (NNA) since 1995, and as Head, NIA Office of Nutrition since 2000.

Dr. Clair Francomano left the Intramural Research Program for a position in the private sector. Her associates in the IRP will be continuing the major thrust of her work, and she will maintain a role as a Special Volunteer so that the NIA can continue to benefit from her expertise in Medical Genetics.

Dr. Mahendra Rao recently departed from the IRP where he was a Senior Investigator in the Laboratory of Neuroscience. He has accepted a position as Vice President in Stem Cell Research for Invitrogen.

INSTITUTE-SPONSORED MEETINGS, WORKSHOPS, CONFERENCES, AND PUBLIC INFORMATION ACTIVITIES

I. Meetings Held

Third Annual Nathan W. Shock Aging Symposium - The NIA Intramural Research Program and Nathan W. and Margaret T. Shock Foundation hosted the 3rd Annual Nathan W. Shock Aging Symposium, “Stem Cells: Regenerative Medicine?,” on September 30, 2005. This one-day (exploratory) symposium was held in Towson, MD. Dr. Gerd Kempermann, internationally recognized for his work on neural stem cell biology, presented NIA’s 16th Annual Nathan W. Shock Lecture, “New Neurons for Old Brains: Lifelong Neuronal Development in the Adult Hippocampus.” Dr. Kempermann is the Research Group Leader of the Neural Stem Cell Unit at the Max Delbrück Center for Molecular Medicine in Berlin-Buch, Germany. His cutting-edge work on the biology of endogenous neural stem cells in the healthy and diseased brain and on the functional relevance of adult neurogenesis has been recognized and appreciated by scientists worldwide. (Contact: Ms. Peggy Grothe, IRP, Ph: 410-558-8012)

Expert Meeting on the Future of the National Long-Term Care Survey (NLTCS) - On October 7, 2005, the Committee on Population and the Committee on National Statistics of the National Research Council hosted this exploratory meeting with funding provided through an NIA/BSR inter-agency agreement. Its purpose was to discuss past and future uses of data from the NLTCS for research on disability trends and dynamics among older Americans, in both community and institutional populations. Topics discussed included comparability of data over time, the uses of panel data, and trends and gaps in the availability of data on disability and its precursors and consequences. Participants included epidemiologists, demographers, statisticians, gerontologists, and other researchers and officials concerned with disability research. (Contact: Dr. John Haaga, BSR, Ph: 301-496-3131.)

Signaling Defects in Immune Aging - A workshop on Signaling Defects in Immune Aging was held on October 24-25, 2005. The purpose of this exploratory workshop was to bring together investigators with scientific expertise in lipid biophysics and plasma membrane structure and composition to provide input on current methodologies that can be applied to study signal transduction. Several investigators who are currently working on signal transduction defects in aging immune cells and the role of oxidative damage and repair of lipid and protein moieties within plasma membranes participated as well. Critical research questions and methodology that could be applied to address these areas were discussed during the course of the workshop. (Contact: Dr. Rebecca Fuldner, BAP, 301-496-6402)

Decision Making and Aging - On November 29, 2005, the Center for the Study of Behavior and Development, in the Division of Behavioral and Social Science, National Academy of Sciences, in conjunction with the Behavioral and Social Behavior Research Program of NIA, conducted a meeting on decision making and aging. Topics discussed included: (1) Neural basis of decision making in older adults, (2) Design of health decision aids for older adults, (3) Role of affect and emotion in decision making by older adults, (4) Effects of age and social context on decision making, and (5) Aging and decision making competence. The meeting was exploratory to help develop directions for future NIA research in this area. (Contact: Dr. Jeffrey Elias, BSR, Ph: 301-402-4156.)

Alzheimer’s Disease “Summit” Meeting - On December 1, 2005, the Neuroscience and Neuropsychology of Aging (NNA) Program of NIA, in conjunction with the National Institute of Neurological Disorders and Stroke (NINDS), the National Institute of Mental Health (NIMH), the National Institute of Biomedical Imaging and Bioengineering (NIBIB), and the National Institute of Nursing Research (NINR), held an Alzheimer’s Disease “Summit” Meeting. The purpose of this exploratory meeting was to lay the groundwork and plan for a larger 2006 meeting which will include scientists from a broad range of disciplines to assess the current state of Alzheimer’s disease research and suggest research directions for the future. The extramural scientists who met for the “Summit” discussed three issues: (1) What are some of the major research questions for which we need answers to get to more effective Alzheimer’s disease diagnostics and therapeutics, (2) What research needs to be done and what infrastructure and other resources need to be provided to get to answers for these questions, and (3) How should the large meeting be structured so that the participants can get an overview of current research and provide advice on future directions? (Contact: Dr. Neil Buckholtz, NNA, Ph: 301-496-9350)

National Health Accounts Workshop - On December 9, 2005, the BSR Program organized exploratory meetings of clinical specialists groups to consider National Health Accounts. The goal of these meetings was to develop a revised set of National Health Accounts using the work of David Cutler and Allison Rosen. National Health Accounts are particularly important to the well being of older populations, who spend a dis­pro­por­tionate amount of income on health maintenance. Research to support the development of National Health Accounts is a high-priority BSR initiative. Escalating health care costs are of interest to policymakers and will likely remain a high policy priority into the future due to the fiscal pressure exerted on social programs by population aging. Escalating costs for Medicare could require significant reform to the program. Having a better understanding of the value of healthcare could lead to a reimbursement system that more efficiently allocates high value medical care to the elderly. (Contact: Dr. John Phillips, BSR, Ph: 301-496-3138.)

NIA Workshop on Molecular and Cellular Mechanisms of Cognitive Aging - On January 9-10, 2006, the Neuroscience and Neuropsychology of Aging Program sponsored this exploratory workshop on cellular and molecular approaches to neural bases of cognitive aging. The main purpose of the workshop was to expose young investigators in the field of molecular and cellular cognition to aging issues/questions in the hope of establishing a new generation of researchers who will apply cutting edge techniques and approaches to cognitive aging. Investigations into the cellular and molecular bases of age-related cognitive change have yielded promising results and opportunities for new avenues of research. For example, electrophysiological techniques to probe tissue slice preparations for changing characteristics of long term potentiation, a model of the cellular basis of memory, have been fruitful. However, while exciting new discoveries about the cellular and molecular bases of learning and memory are increasing and the application of cutting-edge molecular approaches to these questions is rapidly developing, much of the current research is not directed towards applying these discoveries and advances to issues related to aging. Although NIA funds several research programs in this field, there is not a critical mass of junior investigators who are pursuing age-related questions. The invitees were 10 senior investigators and 10 post-docs and/or junior faculty. The meeting featured presentations from senior investigators in the field, poster presentations by the invited young investigators, and meetings of NIA staff with the senior investigators to discuss issues and obstacles for young investigators entering this field and how to overcome them. (Contact: Dr. Molly Wagster, NNA, Ph: 301-594-7768)

II. Meetings Planned

Functional Neuro-Imaging of Sleep/Wake States and Sleep Disorders - This exploratory conference, to be held on March 29-30, 2006, will be sponsored by the Trans-NIH Sleep Research Coordinating Committee (of which NIA is a member and a co-sponsor of this meeting). The objectives of the conference are to (1) review what is known about neuroimaging in sleep deprivation and individual sleep disorders; (2) review emerging neuroimaging technologies used in other domains that may now be ready for addressing relevant questions related to sleep problems and sleep disorders; and (3) determine what is needed to stimulate new research related to neuroimaging to fill gaps in knowledge regarding sleep problems and sleep disorders. (Contact: Dr. Andrew A. Monjan, NNA, Ph: 301-496-9350)

Minority Research in the Basic biology of Aging - In March 2005, an intra-NIH meeting was convened with the purpose of exploring methods to increase diversity in the applicant pool for Biology of Aging Program (BAP) and to increase the relevance of BAP-supported research for reducing health disparities. As a result of that meeting, it was resolved that the next step should be to hold a workshop involving minority-serving institutions (those receiving either Minority Access to Research Careers [MARC] or Research Centers in Minority Institutions [RCMI] funds) and leading investigators conducting research with substantial BAP grant support (R37, P01 or Shock Centers) acting as mentors. BAP will hold an exploratory workshop on this topic sometime in February/March, 2006. The goal of this workshop is to form partnerships between BAP's leading investigators and minority faculty/students, with the immediate goal of obtaining support for training minority faculty/students in biology of aging research via PA-05-015 (NIH Research Supplements to Promote Diversity in Health-Related Research). The longer term goal is to have these minority faculty/students apply for R03, R21 and R01 grants on biology of aging-related topics following their training in biology of aging-research under the tutelage of experienced and successful investigators. (Contact: Dr. Felipe Sierra, BAP, NIA, 301-496-6402).

Genetics Data Sharing - The Behavioral and Social Research Program (BSR) will hold a small workshop to explore issues related to genetic data collections and data sharing in the behavioral and social sciences. The workshop will be held in the spring of 2006. BSR will invite principal investigators of NIA-funded data collection efforts that plan to, or already do, collect DNA, as well as geneticists, ethicists, and social scientists, to participate in this workshop with the following goals: (1) To collect and compile information from ongoing studies that have developed models for genetic and phenotypic data sharing; (2) to collect and compile information relevant for developing a data sharing and repository plan for NIA-funded social and behavioral studies that collect genetic samples; and (3) to host a panel discussion including selected participants and experts with backgrounds in data de-identification and ethics to talk about next steps, concerns, etc. (Contact: Dr. Jennifer Harris, BSR, Ph: 301-496-3138.)

Exploring the Link(s) between Obesity and Alzheimer’s Disease - The goal of this exploratory workshop, planned for spring 2006, is to critically appraise the current state of knowledge on the subject of obesity, metabolic syndrome, and cognition as it relates to Alzheimer’s disease, and to outline possibilities for new research that would increase knowledge about these questions. (Contact: Dr. Suzana Petanceska, NNA, Ph: 301-496-9350)

Metabolomic Approaches to Neurological Disorders - Metabolomics is a technology that aims to identify and quantify the metabolome - the dynamic set of all small molecules present in an organism or a biological sample. In this sense, the technique is distinct from metabolic profiling, which looks for target compounds and their biochemical transformation. The combination of both approaches is an emerging technique for the characterization of biological samples and for drug treatment. Metabolomics has proven to be very rapid and superior to any other post-genomics technology for pattern-recognition analyses of biological samples. Changing steady state concentrations and fluctuations of metabolites that occur within milliseconds are a result of biochemical processes such as signaling cascades: metabolomic techniques are instrumental in measuring these changes rapidly and sensitively. Metabolite data can be complemented by protein, transcript and external (environmental) data, thereby leading to the identification of multiple physiological biomarkers embedded in correlative molecular networks that are not approachable with targeted studies. The goal of this exploratory workshop, planned for spring 2006, is to evaluate the potential usefulness of the metabolomic approach for neuroscience, particularly in developing diagnostics for various neurological disorders and its value in translational research. NIA is a contributing sponsor of the workshop while NINDS is the primary organizer. (Contact: Dr. Suzana Petanceska, NNA, Ph: 301-496-9350)

Alzheimer’s Disease Meeting - On the 100th anniversary of Dr. Alois Alzheimer’s publication of the clinical and neuropathological evaluation of the case study of an individual with the disease eventually named for him, NIA’s Neuroscience and Neuropsychology of Aging (NNA) Program, in conjunction with NINDS, NIMH, NIBIB, and NINR, plan a large meeting with scientists from a broad range of disciplines to assess the current state of Alzheimer’s disease research and to ask for advice and suggestions about research directions for the future. This advisory meeting is planned for summer or fall, 2006. (Contact: Dr. Neil Buckholtz, NNA, Ph: 301-594-7509)

Neuroeconomics - Building on recommendations from teleconferences held in August of 2005, the Behavioral and Social Research Program (BSR) will hold a two-day meeting in March of 2006 to bring together researchers on aging with leading “neuroeconomists” and decision scientists to explore avenues for developing neuroeconomics research focused on lifespan developmental themes. Presentations by researchers in aging in areas of decision research, cognitive neuroscience, and emotion and personality research will serve as stimuli for interdisciplinary discussions of how BSR can develop multi-level economic research aimed at understanding how older adults negotiate important life decisions in social, economic, and health domains. This meeting is intended to facilitate the exploration of research avenues not yet considered by NIA. (Contact: Drs. Jeffrey Elias, Lis Nielsen, John Phillips, BSR, Ph: 301-496-3136.)

GENERAL INFORMATION/STAFF AWARDS

Dr. Luigi Ferrucci, of the Intramural Research Program (IRP), received the NIH Director’s Mentoring Award on July 14, 2005. The award is given to individuals who have demonstrated significant leadership, skill and ability in serving as a mentor to one or more individuals.

Dr. Jack M. Guralnik, Laboratory of Epidemiology, Demography and Biometry, IRP, recently received an honorary Doctor of Medicine from the University of Tampere in Finland. In addition to collaborating with scientists at the facility, he has taught courses in the epidemiology of aging at the university. He was one of six international scientists to receive the honor.

Florence S. Mahoney Lecture on Aging - John Hardy, Ph.D., Chief of the Laboratory of Neurogenetics at NIA, gave the 20th Florence S. Mahoney Lecture on Aging on Dec. 14th at NIH in Bethesda, MD. The lecture, “Neurodegeneration: Too Much of a Bad Thing Kills You,” was sponsored by the NIA and is part of the prestigious NIH Director’s Wednesday Afternoon Lecture Series. (Contact: Ms. Anne Decker, OCPL, Ph: 301-496-1781)

Publications

The following two publications were funded by BSR under an NIH Task Order with the National Academy of Sciences:
Expanding Access to Research Data, National Research Council of the National Academies.
When I’m 64, National Research Council of the National Academies.

The following new publications were updated or reprinted:

• Progress Report on Alzheimer’s Disease 2004-2005
• Talking with Your Doctor
• Tip Sheet: NIA Online Resources; Tip Sheet: Understanding Risk
• Alzheimer’s Disease Centers Directory
• Connections, Vol. 13, No. 1-2
• Exercise Guide
• Genes, Lifestyles, and Crossword Puzzles: Can AD be Prevented?
• AD Fact Sheet
• Age Pages: Arthritis Advice, A Good Night’s Sleep, Forgetfulness, Hypothermia, Hyperthermia, Urinary Incontinence, Menopause, Alcohol, Sexuality, Hearing, Eyes, Health Quackery
• NIA Publications CD-ROM

NIA News Releases/Outreach

• Nine press releases were distributed. Clips were viewed by an estimated 21 million people in print.
• Public outreach activities included participation in a number of meetings and events where the NIA exhibit was featured or publications distributed -- the Tom Joyner Family Reunion, Black Family Reunion, Meals on Wheels Association, National Association of Community Health Centers, ADC/ADCS/ADNI meetings, North American Menopause Society, Hispanic Health Fairs (10 sites), National Association of Biology Teachers Regional Conference, National Middle School Association Regional Conference, National Science Teachers Association Regional Conference, U.S. Senate Elder Care Fair, University of Kentucky’s Branching Out/African Americans and AD conference, Washington University’s Leonard Berg Symposium, UT Southwestern’s AD Genetics meeting, Medicine for the Public lecture, Society for Neuroscience, Gerontological Society of America, and the Society for Teachers of Family Medicine.

Award
The NIA publication “What’s Your Aging IQ?” received an Award of Excellence from the National Association of Government Communicators.

(Contact: Ms. Vicky Cahan, OCPL, Ph: 301-496-1752)

New Notices and Initiatives Relevant to National Institute on Aging (NIA)
Excerpts from the NIH GUIDE- from August 26, 2005 – December 21, 2005
Includes Notices and Initiatives (Requests for Applications (RFAs) and Program Announcements (Pas), published since October
2005 Council presentation of the Director’s Status Report (DSR) to the National Advisory Council on Aging (NACA). Also check our
NIA website for “Funding Opportunities” at:

www.nia.nih.gov/GrantsAndTraining/FundingOpportunities/CurrentFundingOpportunities.htm
(Shown here are selected Notices and Initiatives relevant to NIA/National Institutes of Health/DHHS).

NOTICES ISSUED BY NIA
(Notices are sorted by release date.  Most recent Notices are at the top of this list.)

NOTICES ISSUED BY NIH (Central)
(Notices are sorted by release date.  Most recent Notices are at the top of this list.)

 NOTICES ISSUED BY OTHER INSTITUTES/CENTERS AT NIH (with NIA involvement)
(Notices are sorted by release date.  Most recent Notices are at the top of this list.)

FUNDING OPPORTUNITIES – RFAs and PAs –issued by NIA
(Notices are sorted by release date.  Most recent notices are at the top of this list.)

FUNDING OPPORTUNITIES – Other RFAs AND PAs with NIA involvement, but issued by or other Institutes at NIH
(Notices are sorted by release date.  Most recent notices are at the top of this list.)