Scientific Supercomputing at the NIH
The Helix Systems group is responsible for the planning and management of high-performance computing systems specifically for the intramural NIH community. These systems include Helix, a multiprocessor shared-memory system for interactive use; Biowulf, a 6300+ processor Linux cluster; and Helixweb, which provides a number of scientific tools via the web. We provide access to a wide range of computational applications for molecular and structural biology, mathematical and graphical analysis, and other scientific fields.



Recent Publications Citing Helix and Biowulf:

Thermostat Artifacts in Replica Exchange Molecular Dynamics Simulations
Edina Rosta, Nicolae-Viorel Buchete and Gerhard Hummer
J. Chem. Theory and Computation , published online 9 April (2009)

Pathway analysis by adaptive combination of P-values
Kai Yu, Qizhai Li, Andrew W. Bergen, Ruth M. Pfeiffer, Philip S. Rosenberg, Neil Caporaso, Peter Kraft, Nilanjan Chatterjee
Genetic Epidemiology , published online 30 Mar (2009)

Comparison of the Extended Isotropic Periodic Sum and Particle Mesh Ewald Methods for Simulations of Lipid Bilayers and Monolayers
Richard M. Venable, Linda E. Chen and Richard W. Pastor
J. Phys. Chem B , published online 7 April (2009)

Genetic background comparison using distance-based regression, with applications in population stratification evaluation and adjustment
Qizhai Li, Sholom Wacholder, David J. Hunter, Robert N. Hoover, Stephen Chanock, Gilles Thomas, Kai Yu
Genetic Epidemiology , published online 12 Jan (2009)