N C C A M: The National Center for Complementary and Alternative Medicine. Expanding horizons of health care

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Research Results

Major Clinical Trial Results


Ginkgo Evaluation of Memory (GEM):

The largest clinical trial to evaluate the effect of the dietary supplement, Ginkgo biloba, on the development of dementia and Alzheimer's. Published in JAMA 2008. More

A Knee Joint

Glucosamine/Chondroitin Arthritis Intervention Trial (GAIT):

A primary and ancillary study on glucosamine and/or chondroitin for the treatment of pain and structural damage associated with knee osteoarthritis. Published in NEJM 2006 and Arthritis Rheum 2008. More


Echinacea for the Prevention and Treatment of Colds in Adults

A two phase, randomized placebo-controlled trial that tested different preparations of Echinacea (E. angustifolia) for the prevention and treatment of common colds in adults. Published in NEJM 2005. More

Acupuncture of the Knee

Acupuncture for Osteoarthritis of the Knee

This large, landmark study examined the ability of acupuncture to relieve pain and improve function in people with osteoarthritis of the knee. Published in Ann Intern Med 2004. More

St. John's Wort

St. John's Wort and Depression

A randomized, double-blind trial that compared a standardized preparation of St. John's Wort (H. perforatum) with a placebo and sertraline, for the treatment of major depression. Published in JAMA 2002. More

Recent Trial Results Spolighted


Study Finds Creatine Does Not Enhance Strength-Building Effects of Resistance Training in HIV Patients

(Feb 2009)
Doctor speaking to patient.

Translating CAM Research Results Into Clinical Practice…

(Apr 2009)

Grape Seed Extract May Help Neurodegenerative Diseases

(Feb 2009)

Acupuncture Shows Possible Effect for Tension Headaches

(Jan 2009)
Electroacupuncture needles in arm

Electroacupuncture Relieves Cancer Pain in Laboratory Rats

(Jan 2009)
Doctor using acupuncture on a patient.

Brain-Imaging Study Finds Different Mechanisms Underlying Pain Relief From Electroacupuncture and Placebo

(Dec 2008)
Cocoa beans in a cacao pod

NCCAM Researchers Investigate Effects of Cocoa in People With Hypertension

(Dec 2008)

More Research Results


More Published Research