Description

The FLOSS software package uses input and output files from the MERLIN linkage analysis package (Abecasis et al, 2002) to perform an ordered subset analysis using either nonparametric linkage analysis z-scores or linear allele sharing model LOD scores.

FLOSS was developed by Brian Browning at the University of Auckland.

Version

1.4

Sample session

Sample input files can be downloaded from http://www.stat.auckland.ac.nz/~browning/floss/download.htm#sample_files.

% merlin -d test.dat -p test.ped -m test.map -ff --npl --grid:2 --perFamily
% java -jar /usr/local/floss_1.4/floss/cov.jar -d test.dat -p test.ped -o test.cov
% java -jar /usr/local/floss_1.4/floss/floss.jar -c test.cov -merlin merlin.lod \
-o floss.test --npl

Documentation

http://www.stat.auckland.ac.nz/~browning/floss/floss.htm