[HBPP Membership Roster] [HBPP Meeting Rosters]

The Hepatobiliary Pathophysiology [HBPP] study section reviews applications involving pathophysiology and treatment of inherited and acquired viral and non viral hepatobiliary diseases; molecular biology of liver function under physiologic and pathophysiologic states; mechanisms of  liver injury, repair, regeneration, and transplantation; liver cell biology, immunology and inflammation; cholesterol and bile salt metabolism; hepatobiliary transporters, hepatic protein metabolism, ion channels; and alcohol metabolism and disease.

Specific areas covered by HBPP:

• The use of isolated parenchymal and non-parenchymal cells of the liver as they relate to the pathogenesis of liver disease and progenitor cell therapy of genetic and acquired hepatobiliary diseases. Genetic basis of liver diseases.
• Mechanisms of bile formation, bile salt synthesis and cholestasis; mechanisms of hepatic cholesterol and lipid metabolism and regulation of lipoprotein genes; physiologic mechanisms of hepatobiliary transport and hepatic protein metabolism.
• Inflammatory response of the liver to injury or infection and mechanism of hepatocyte injury including immune response, oxidative stress, apoptosis, pro- and anti-inflammatory mediators. Signal transduction pathways and neuromediators.
• Liver injury, repair, regeneration, growth, differentiation, development, aging, and transplantation; Liver dysplasia and pre-neoplasia, mechanisms of transformation; immortalization and mutagenesis; Liver ischemia-reperfusion injury and regulation of splanchnic blood flow as it pertains to mechanisms of portal hypertension.
• Cellular and molecular mechanisms, gene regulation, pathogenesis, and treatment of liver diseases, such as, fibrosis and cirrhosis; cholangiopathies; gallstones and gallbladder disease; viral hepatitis as it relates to the pathogenesis of hepatobiliary disease; non-alcoholic fatty liver and alcoholic liver diseases.

Study sections with most closely related areas of similar science listed in rank order are:

Xenobiotic and Nutrient Disposition and Action [XNDA] 
Cancer Etiology [CE] 
Innate Immunity And Inflammation [III] 
Integrative Nutrition and Metabolic Processes [INMP] 
Virology A and Virology B [VIRA & VIRB]