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Genome Technology BranchInvestigators in the Genome Technology Branch (GTB) study the structure and function of genomes in disease and normal states. Over the years, GTB researchers have developed world-class expertise in a wide range of genomic techniques, including the mapping and sequencing of mammalian chromosomes, gene isolation, systematic mutagenesis, developmental genomics, and computational analysis of DNA and protein sequences. This work has been applied to the development, testing, and implementation of a range of innovative technologies for performing genome sequencing, screening, and analysis. GTB investigators are actively studying the genetic causes of rare disorders, such as hereditary deafness, progeria, and peripheral neuropathies. They also are studying genetic contributions to more common conditions, such as type 2 diabetes and neural tube defects, and are investigating how particular genes may influence normal health and even longevity. GTB houses core units and centers that provide genomic services to NHGRI and the broader National Institutes of Health (NIH) community. Many intramural scientists at other NIH Institutes have tapped into GTB's expertise in large-scale DNA sequencing and its applications, and others have benefited from GTB's developments in computational genomics. GTB investigators are involved in a number of joint ventures with other NIH Institutes to develop resources for the genomic research community, including numerous genome analysis tools and resources that are freely available on the NHGRI website. Senior InvestigatorsEric D. Green, M.D., Ph.D. Lawrence C. Brody, Ph.D. Elizabeth G. Nabel, M.D. InvestigatorsShawn Burgess, Ph.D. Laura L. Elnitski, Ph.D. Elliott Margulies, Ph.D. Associate InvestigatorsChristopher P. Austin, M.D. Andy Baxevanis, Ph.D. Robert W. Blakesley, Ph.D. Gerard Bouffard, Ph.D. Settara C. Chandrasekharappa, Ph.D. Jim Inglese, Ph.D. James C. Mullikin, Ph.D. Tyra Wolfsberg, Ph.D. Research Project Web SitesBreast Cancer Information Core Human Chromosome 7 Mapping and Sequencing
Last Updated: February 6, 2009 |
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