On May 17, I added links to the Human Gene Nomenclature Committee names (HGNC).
Last revised May 17, 2007
I have tried to make this table as up to date as possible. Entrez Gene, OMIM, Unigene and all other links have been checked and updated.
I have included seven gene cluster maps that show human, mouse and rat compared (red links in the first column).
These maps are further described in:
Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes
Pharmacogenetics 14, 1-18 2004
The Entrez Gene site has extensive data and links for intact sequences and some pseudogenes.
For a complete set of human P450 sequences including pseudogenes go to the FASTA file
All human P450 genes and all P450 pseudogenes are included in this table.
This table contains more than 700 links to human P450 data, including known crystal structures.
CYP names in column 1 are linked to their protein sequences, including the pseudogenes.
X at the end of a CYP name means that name has been discontinued and replaced by a new name
Pseudogenes are named using suffixes to specify the four types of pseudogenes defined as:
P is a full length or near full length pseudogene, it may be near or far from other P450s.
-ps is equivalent to P, but it is required nomenclature for mouse full length pseudogenes.
-de stands for detritus exons (found near other full length genes).
-se stands for solo exons, one or a few exons found distant from a P450 gene.
-ie stands for internal exons, duplicate exons found inside some P450 genes.
CYP |
Genbank |
RefSeq mRNA |
Genomic Assemblies |
RefSeq Protein |
OMIM |
HGNC |
Unigene |
EntrezGene |
comments |
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
15q24.1 |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
15q24.1 |
|||||||
no entry |
no entry |
no entry |
no entry |
no entry |
9q21.12 43% identical to 1A2, ortholog to Danio 1D1 |
||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
601771 see additional entries under phenotypes in the Entrez Gene link |
2p22.2 |
||||||
2A
|
see related sequences under the Entrez Gene link |
no entry |
no entry |
no entry |
19q13.2 |
||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
19q13.2
Structures |
|||||||
no entry |
no entry |
no entry |
no entry |
2A6*3 allele |
|||||
see related sequences under the Entrez Gene link |
no entry |
see reference assembly under the Entrez Gene link |
no entry |
19q13.2 wt seq |
|||||
see related sequences under the Entrez Gene link |
19q13.2 hybrid, exon 8 from 2A18PC |
||||||||
see reference assembly under the Entrez Gene link |
no entry |
19q13.2 alt. splice, exon 2 deleted |
|||||||
no entry |
see reference assembly under the Entrez Gene link |
no entry |
no entry |
identical to 2A18PN |
|||||
no entry |
see reference assembly under the Entrez Gene link |
no entry |
no entry |
identical to 2A18PN |
|||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
no entry |
19q13.2 |
||||||
no entry |
no entry |
no entry |
no entry |
no entry |
opposite end of 2A18PN |
||||
no entry |
no entry |
no entry |
formerly 2A7PT and 2A7PC |
||||||
2B |
no entry |
no entry |
no entry |
no entry |
19q13.2 |
||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
19q13.2 |
|||||||
see related sequences under the Entrez Gene link |
no entry |
see reference assembly under the Entrez Gene link |
no entry |
no entry |
HIIB3 |
||||
2B7P2X |
no entry |
no entry |
no entry |
no entry |
no entry |
exon 1 only, error = 2B6 |
|||
2B7P3X |
no entry |
no entry |
no entry |
no entry |
no entry |
exon 1 only, error = 2B6 |
|||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
10q23.33
Structures |
|||||||
no entry |
no entry |
no entry |
no entry |
no entry |
detritus exon 6 near 2C8 |
||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
10q23.33
Structures |
|||||||
no entry |
no entry |
no entry |
no entry |
no entry |
detritus exon 1 near 2C9 |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
detritus exons 2,3 near 2C9 |
||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
10q23.33 |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
10q23.33 |
|||||||
no entry |
no entry |
no entry |
no entry |
no entry |
solo exons 1,2,3 between 2C19 and 2C9 |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
10q24.31 pseudogene 5Mb upstream of 2C8 |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
solo exon 7, 2q24.3 = old CYP2C56P |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
solo exons 1,2 10q21.3 = old CYP2C61P |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
solo exon 1, 21q21.2 = old CYP2C63P |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
solo exon 1, Xq28 = old CYP2C64P |
||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
deleted in genome assembly 22q13.1
Structures |
|||||||
see sequences under the Unigene link |
no entry |
no entry |
no entry |
no entry |
no entry |
alt. spliced 2D7 polymorphic full length 22q13.1 |
|||
see related sequences under the Entrez Gene link |
no entry |
see reference assembly under the Entrez Gene link |
no entry |
no entry |
no entry |
2D cluster at 22q13.2 |
|||
no entry |
no entry |
no entry |
no entry |
97.4% to 2D7P on a 44kb XbaI frag. |
|||||
no entry |
see reference assembly under the Entrez Gene link |
no entry |
no entry |
no entry |
87.3% to 2D7P |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
96.8% to 2D7P on a 44kb XbaI frag. Also called 2D8BP |
||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
10q26.3 |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
19q13.2 |
|||||||
see related sequences under the Entrez Gene link |
no entry |
see reference assembly under the Entrez Gene link |
no entry |
no entry |
no entry |
missing N-term |
|||
see related sequences under the Entrez Gene link, also S80998 S80999 |
no entry |
see reference assembly under the Entrez Gene link |
no entry |
no entry |
94% missing exons 4, 5, 6 |
||||
see related sequences under the Entrez Gene link |
no entry |
see reference assembly under the Entrez Gene link |
no entry |
no entry |
no entry |
in frame stops and frameshifts |
|||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
1p32.1 |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
11p15.2 |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
no entry |
19q13.2 |
||||||
no entry |
see reference assembly under the Entrez Gene link |
no entry |
no entry |
2T1 rat is expressed |
|||||
no entry |
see reference assembly under the Entrez Gene link |
no entry |
no entry |
no entry |
2T1 rat is expressed |
||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
4q25 synonym P450TEC |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
no entry |
7p22.3 NP_seq incomplete |
||||||
no entry |
no entry |
no entry |
no entry |
no entry |
3q27.1 = old CYP2D31P, 75% to mouse 2ab1 |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
6p12.3 = old CYP2C57P 68% to rat 2AC1 (XM_236969.1) |
||||
3A |
see related sequences under the Entrez Gene link |
no entry |
see reference assembly under the Entrez Gene link |
no entry |
no entry |
no entry |
3A subfamily entry |
||
3A3X |
no entry |
no entry |
no entry |
no entry |
no entry |
discontinued no. = 3A4 |
|||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
7q22.1
Structures |
|||||||
no entry |
no entry |
no entry |
no entry |
no entry |
7q22.1 partial internal exon |
||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
7q22.1 = wt CYP3A5 |
|||||||
see also related sequences under the Entrez Gene link |
no entry |
see reference assembly under the Entrez Gene link |
no entry |
no entry |
no entry |
no entry |
CYP3A5_v2 = alt. splice of 3A5, = old 3A5P1, but not a pseudogene |
||
no entry |
no entry |
no entry |
no entry |
no entry |
CYP3A5_v3 = alt. splice of
3A5, = old CYP3A5P2, but not a pseudogene
|
||||
no entry |
no entry |
no entry |
no entry |
detritus exon 13 near 3A5 = old CYP3A51P |
|||||
no entry |
no entry |
no entry |
no entry |
detritus exons 1,2 near 3A5 |
|||||
see related sequences
under the Entrez Gene link |
see reference assembly
under the Entrez Gene link |
7q22.1 |
|||||||
no entry |
no entry |
no entry |
no entry |
detritus exons 1,2 near
3A7 |
|||||
see related sequences
under the Entrez Gene link |
see reference assembly
under the Entrez Gene link |
7q22.1 isoform 1 |
|||||||
see related sequences
under the Entrez Gene link |
see reference assembly
under the Entrez Gene link |
7q22.1 isoform 2 |
|||||||
see related sequences
under the Entrez Gene link |
see reference assembly
under the Entrez Gene link |
7q22.1 isoform 3 |
|||||||
no entry |
no entry |
no entry |
no entry |
no entry |
detritus exon 1 near 3A43 |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
detritus exons 4,6 near
3A43 = old 3A52P, 3A53P |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
solo exon 2, = old
CYP3A54P near CYP2W1 |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
solo exon 5, = old
CYP3A55P near CYP2W1, 214kb from 3A54P |
||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
1p33 |
|||||||
4A20X |
no entry |
no entry |
no entry |
no entry |
no entry |
no entry |
no entry |
restored to old name 4Z1 |
|
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
no entry |
1p33 95% identical to 4A11 |
||||||
no entry |
no entry |
no entry |
no entry |
no entry |
solo exon 12, = old CYP4A26P |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
solo exon 1 |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
solo exon 12, = old CYP4A27P |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
solo exon 2 |
||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
1p33 |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
19p13.12 |
|||||||
no entry |
no entry |
no entry |
no entry |
no entry |
exon 12 downstream of 4F2 = old CYP4F36P |
||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
19p13.12 |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
no entry |
19p13.12 |
||||||
no entry |
no entry |
no entry |
no entry |
no entry |
19p13.12 35kb upstream of 4F11 |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
19p13.12 between 4F3 and 4F12 |
||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
no entry |
19p13.12 |
||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
no entry |
19p13.12 |
||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
no entry |
19p13.12 Entrez Gene name is incorrectly called CYP2E2 |
||||||
no entry |
no entry |
no entry |
no entry |
no entry |
19p13.12 between 4F22 and 4F8 |
||||
no entry |
no entry |
no entry |
no entry |
19p13.12 between 4F12 and 4F2 |
|||||
no entry |
no entry |
no entry |
no entry |
no entry |
9q13 = old 4F25P, in 3 prime UTR of AK125850, inside PTGES3 |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
9p13.3 = old 4F26P |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
2q21.1 = old 4F27P |
||||
no entry |
see reference assembly under the Entrez Gene link |
no entry |
no entry |
no entry |
21q11.2 = old 4F29P
synonym CYP4F3LP |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
2q11.1 = old CYP4F32P |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
9p13.1 = old CYP4F33P |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
13q11 = old CYP4F34P |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
18p11.21 = old CYP4F35P |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
2q21.1 = old CYP4F30P |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
2q21.1 = old CYP4F31P |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
2q21.1 = old CYP4F43P |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
8p11.1 = old CYP4F44P |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
9p11.2 = old CYP4F45P
identical to CYP4F-se1[6:8] |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
9p11.2
identical to CYP4F-se1[6:8] |
||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
4q35.2 = old 4AH1, Bietti crystalline corneoretinal dystrophy |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
no entry |
1p33 not in Build 33 |
||||||
see reference assembly under the Entrez Gene link |
no entry |
1p33 formerly 4A20 |
|||||||
see related sequences under the Entrez Gene link |
no entry |
see reference assembly under the Entrez Gene link |
no entry |
no entry |
full pseudogene between 4B1, 4A11, 94% to 4Z1 |
||||
4AH1X |
no entry |
no entry |
no entry |
no entry |
no entry |
no entry |
no entry |
renamed 4V2 |
|
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
TBXAS1 thromboxane synthase form-I 7q34 |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
thromboxane synthase form-II 7q34 |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
8q12.1 |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
8q12.3 |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
prostacyclin synthase 20q13.13 PTGIS
Structures |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
3p22.1 |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
15q24.1 |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
8q24.3 |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
8q24.3, missing coding exon 8, including the heme signature |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
8q24.3, Corticosterone Methyloxidase Type I and Type II Deficiency, Glucocorticoid-Remediable Aldosteronism |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
10q24.32 |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
15q21.2, aromatase, hereditary gynecomastia |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
15q21.2, aromatase, hereditary gynecomastia, includes untranslated exon 2a that makes a longer 5 prime UTR |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
no entry |
2q33.2, full length |
||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
no entry |
2q33.2, truncated variant |
||||||
see related sequences under the Entrez Gene link |
no entry |
see reference assembly under the Entrez Gene link |
no entry |
no entry |
no entry |
6p21.33 pseudogene |
|||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
6p21.33 CYP21 |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
20q13.2 |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
10q23.33 P450RAI-1, full length |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
10q23.33 P450RAI-1, truncated 69 amino acids at N-term |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
2p13.2 P450RAI-2 |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
10q23.33 |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
2q35 |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
12q14.1 |
|||||||
see related sequences under the Entrez Gene link, and AC027142 |
see reference assembly under the Entrez Gene link |
no entry |
2q14.3 FLJ16008, Entrez Gene seq is short |
||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
6p12.3 |
|||||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
14q32.2 |
|||||||
no entry |
no entry |
no entry |
no entry |
no entry |
1p33 12Mb from CYP2J2 = old CYP46A4P |
||||
see related sequences under the Entrez Gene link |
see reference assembly under the Entrez Gene link |
7q21.2 |
|||||||
no entry |
no entry |
no entry |
no entry |
no entry |
3p12.2 |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
13q12.3 |
||||
no entry |
no entry |
no entry |
no entry |
no entry |
6q24.3 |