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Home » About the NTP » NTP Quarterly Newsletter » Attachment - 8th BRC Summary Table
Attached Table
CHEMICAL/ CAS NUMBER |
PRIMARY USES |
PROPOSED TO BE LISTED AS: |
AZACITIDINE/ 320-67-2 |
Used as a cytostatic agent in the treatment of acute leukemia. | Reasonably Anticipated to be a Human Carcinogen |
p-CHLORO-o-TOLUIDINE and its HCl salt/ 95-69-2 |
Used to produce azo dyes for cotton, silk acetate and nylon and as intermediate in production of Pigment Red 7 and Pigment Yellow 49. Also an impurity in and a metabolite of the pesticide chlordimeform. | Reasonably Anticipated to be a Human Carcinogen |
CHLOROZOTOCIN/ 54749-90-5 |
Used as a cytostatic agent in the treatment of cancers of the stomach, large intestine pancreas and lung, melanoma, and multiple myeloma. | Reasonably Anticipated to be a Human Carcinogen |
CYCLOSPORIN/ 59865-13-3 |
Used as an immunosuppressive agent in the prevention and treatment of graft-vs-host reactions in bone marrow transplantation and for the prevention of rejection of kidney, heart, and liver transplants. | Known to be a Human Carcinogen |
DANTHRON/ (1,8-Dihydroxy- anthraquinone 117-10-2 |
Used as a laxative and as an intermediate in the manufacture of dyes | Reasonably Anticipated to be a Human Carcinogen |
1,6-DINITROPYRENE/ 42397-64-8 |
Not used commercially, detected in ambient atmospheric samples and as a constituent of diesel exhaust. | Reasonably Anticipated to be a Human Carcinogen |
1,8-DINITROPYRENE/ 42397-65-9 |
Not used commercially, detected in ambient atmospheric samples and as a constituent of diesel exhaust | Reasonably Anticipated to be a Human Carcinogen |
DISPERSE BLUE 1/ (1,4,5,8-Tetra- aminoanthraquinone) 2475-45-8 |
Used as an anthraquinone based dyestuff in hair color formulations and in coloring fabrics and plastics | Reasonably Anticipated to be.a Human Carcinogen |
FURAN/ 100-00-9 |
Used as an intermediate in the synthesis and production of other organic compounds | Reasonably Anticipated to be a Human Carcinogen |
o-NITROANISOLE/ 91-23-6 |
Used as a precursor in the synthesis of o-anisidine which is used in the manufacture of over100 azo dyes. | Reasonably Anticipated to be a Human Carcinogen |
6-NITROCHRYSENE/ 7495-02-8 |
Not used commercially, detected in ambient atmospheric samples. | Reasonably Anticipated to be a Human Carcinogen |
1-NITROPYRENE/ 5522-43-0 |
Not used commercially, detected in ambient atmospheric samples and as a constituent of diesel and gasoline engine exhaust. | Reasonably Anticipated to be a Human Carcinogen |
4-NITROPYRENE/
57835-92-4 | Not used commercially, detected in ambient atmospheric samples. | Reasonably Anticipated to be a Human Carcinogen |
THIOTEPA/
52-24-4 |
Used as a cytostatic agent in the treatment of lymphomas and a variety of solid tumors, such as breast and ovary. It has also been used at high doses in combination chemotherapy with cyclophosphamide in patients with refractory malignancies treated with autologousbone transplantation. | Known to be a Human Carcinogen |
1,2,3-TRICHLOROPROPANE/ 96-18-4 | Used as a polymer crosslinking agent, paint and varnish remover, solvent and degreasing agent. It has been found as an impurity in certain nematicides and soil fumigants and has been detected in drinking and ground water in various parts of the United States. | Reasonably Anticipated to be a Human Carcinogen |
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