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Summaries & Associations of Study Results
Summaries & Associations of Study Results
Home » Study Results & Research Projects » Summaries & Associations of Study Results » TR-347 d-Limonene
CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
---|---|---|---|---|
D-LIMONENE 5989-27-5 |
04/18/88 | INDUSTRIAL SOLVENT, FLAVOR & FRAGRANCE ADDITIVE OBTAINED FROM CITRUS FRUIT | Gavage FR: 0,300,600, MR: 0,75,150, FM: 0,500,1000, MM: 0,250,500 MG/KG/50 PER GROUP | Microbiological Associates |
LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
MR: CLEAR EVIDENCE | KIDNEY TUBULAR CELL: ADENOMA 0/50 4/50 8/50 OR ADENOCARCINOMA 0/50 4/50 3/50 | |||
NON-NEOPLASTIC LESIONS: | KIDNEY: PAPILLA, MINERALIZATION 7/50 43/50 48/50; HYPERPLASIA, TUBULAR CELL 0/50 4/50 7/50; HYPERPLASIA, EPITHELIAL 0/50 35/50 43/50; INCREASED SEVERITY OF NEPHROPATHY | |||
FR: NO EVIDENCE | ||||
MM: NO EVIDENCE | ||||
FM: NO EVIDENCE |
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