Summaries & Associations of Study Results
TR-437 Hexachlorocyclopentadiene
Target Organs and Levels of Evidence
NTP Technical Report Number 437
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| HEXACHLOROCYCLOPENTADIENE 77-47-4 |
06/22/93 | CHEMICAL INTERMEDIATE FOR INSECTICIDES. FLAME RETARDANT. (TDB) | Inhalation R:0,.01,.05,.2PPM M:0,.01,.05,.2,.5PPM/50 PER GROUP | Battelle Northwest Laboratory |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | LUNG: BRONCHIOLE PIGMENTATION; PERIBRONCHIOLAR PIGMENTATION | |||
| NASAL CAVITY: PIGMENTATION | ||||
| TRACHEA: PIGMENTATION | ||||
| FR: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | LARYNX: SQUAMOUS METAPLASIA | |||
| LUNG: BRONCHIOLE PIGMENTATION; PERIBRONCHIOLAR PIGMENTATION | ||||
| NASAL CAVITY: PIGMENTATION | ||||
| TRACHEA: PIGMENTATION | ||||
| MM: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | LUNG: MUCOSAL PIGMENTATION | |||
| NASAL CAVITY: SUPPURATIVE INFLAMMATION; MUCOSAL PIGMENTATION | ||||
| TRACHEA: MUCOSAL PIGMENTATION | ||||
| FM: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | LUNG: MUCOSAL PIGMENTATION | |||
| NASAL CAVITY: SUPPURATIVE INFLAMMATION; MUCOSAL PIGMENTATION | ||||
| TRACHEA: MUCOSAL PIGMENTATION | ||||
Web page last updated on February 10, 2006
