Ordering Information
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WB: untreated (lane 1) and lambda phosphatase-treated (lane 2) Fetal bovine heart endothelial cell lysate was probed with anti-phospho-eNOS (1:1000) ...
Anti-phospho-eNOS/NOS III (Ser116)
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| B, H | WB | Rabbit | Affinity Purified | Polyclonal Antibody |
UniProt Number:
UniProt Summary
FUNCTION: SwissProt: P29474 # Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. No mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.
COFACTOR: Heme group. & Binds 1 FAD. & Binds 1 FMN. & Metrahydrobiopterin (BH4). May stabilize the dimeric form of the enzyme.
SIZE: 1203 a ... see more »
COFACTOR: Heme group. & Binds 1 FAD. & Binds 1 FMN. & Metrahydrobiopterin (BH4). May stabilize the dimeric form of the enzyme.
SIZE: 1203 a ... see more »
Entrez Gene Number:
Description:
Anti-phospho-eNOS/NOS III (Ser116)
Specificity:
eNOS/NOS III phosphorylated on serine 116
Key Applications:
Western Blotting
Species Reactivity:
- Bovine
- Human
Isotype:
IgG
Immunogen:
peptide corresponding to amino acids 106-118 of human eNOS/NOS III (Ser116) (PRKLQGRPpSPGPP-C)
Modifications:
Phosphorylation
Molecular Weight:
132kDa
Presentation:
0.2M Tris-glycine, pH 7.4, 0.15M NaCl, 0.1mM EDTA, and 0.05% sodium azide before the addition of glycerol to 30%
Storage Conditions:
1 year at -20°C
Gene Symbol:
- NOS3
- cNOS
- ECNOS
- eNOS
- EC-NOS
- NOSIII
Quality Assurance:
routinely evaluated by immunoblot in fetal bovine heart endothelial cell lysate
Antibody Category:
Neuroscience
Antibody Sub-Category:
Oxidative Stress
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Descriptive Text:
Trade Name:
Upstate (Millipore)
Purification Method:
immunoaffinity chromatography
Format:
Affinity Purified
Product Overview:
Note: ADMA (Catalog #19-169) and NMMA (Catalog #19-170) are inhibitors of NOS
Antibody Type:
Polyclonal Antibody
Host:
Rabbit